人工心脏瓣膜材料细菌粘附的初步研究

Primary Study of Bacterial Adhesion of Prosthetic Valve Materials

在体外采用平板计数方法测定了金黄色葡萄球菌、表皮样葡萄球菌、大肠杆菌、绿脓杆菌及白色念珠菌等5种细菌对医用涤纶及热解碳的粘附．结果表明：实验所用细菌对两种人工心脏瓣膜材料均有粘附性，其对涤纶的粘附均明显强于热解碳．细菌的粘附力差异较大，并明显地受材料理化性质的影响，金黄色葡萄球菌对涤纶的粘附力最强，绿脓杆菌对热解碳的粘附力最强．

The adhesion of Staphylococcus aureus,Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa and Candida albicans to Dacron and pyrolite carbon was measured in vitro with plate counting. The ex-perimental result showed:the bacterials used in the experiment have adhesion to prosthetic valve materials;the bac-terials have stronger adhesion to Decron than to Pyrolite carbon ;the bacterial adhesive capacity is significantly dif-ferent and is affected by mechanical and chemical nature of biomaterials; Staphylococcur aureus has the strongest adhesion to Dacron,and Pseudomonas aeruginosa has the strongest adhesion to pyrolite carbon in all bacterials.