高血压病患者左室重构的研究

Left Ventricular Reconstruction Study in Hypertension Patients

评价高血压病患者左室重构和心功能的变化，应用超声心动图对１４６例原发性高血压病人的左心结构和功能进行研究，并与７２例正常作对照结果显示：左室正常构型占５３％，向心性重构占１５％，向心性肥厚占１３％，离心性肥厚占１９％向心性肥厚组左室舒张功能受损最重，离心性肥厚组收缩功能较其它组降低向心性肥厚和离心性肥厚组的年龄和病程无显著差异，但均大于左室正常构型和向心性重构组向心性肥厚和离心性肥厚组的血压均显著高于其它构型组，离心性肥厚组ＴＰＲ无增高，其余三种构型组均明显升高向心性肥厚和离心性肥厚组ＬＶＥＳＳ均显著高于左室正常构型和向心性重构组结果表明。

To assess the left ventricle remodeling and cardiac function in hypertension patients, echocardiography was applied in studying the left ventricular structure and cardiac function among 146 cases of primary hypertension, with 72 normal cases serving as a contrast. The results were shown as follows: Normal left ventricle accounted for 53%; concentric remodeling, for 15%; concentric hypertrophy, for 13%; and eccentric hypertrophy, for 19% . Concentric hypertrophy group suffered the most serious damage of left ventricular distolic function, whereas eccentric hypertrophy one had a lower systolic functions than the other groups. The age and disease course revealed no difference between concentric and eccentric groups, but they gave bigger figures in comparison with the normal left ventricle and concentric remodeling groups. Blood pressure was evidently higher in concentric and eccentric hypertrophy groups than in the other pattern groups. In the eccentric hypertrophy group there was not any TPR increase, which was noticeably seen in the other three groups. LVESSS was markedly higher in the concentric and eccentric groups than in the normal left ventricle and concentric remodeling groups. The results suggested that the left ventricular reconstruction paralleled the systemic hemodynamics and ventricular load.