滴通鼻炎水的抗炎、缩血管作用及对血压的影响研究

Study on the effects of Ditong Rhinitis Water on the inflammation,the blood vessel contraction and the blood pressure

目的:观察滴通鼻炎水的抗炎、缩血管作用以及对血压的影响。方法:用二甲苯造成小鼠耳廓肿胀,观察滴通鼻炎水的抗炎作用;并且通过大鼠肠系膜滴药观察滴通鼻炎水对大鼠肠系膜微循环的缩血管作用和对全身血压的影响。结果:滴通鼻炎水有较好的抗炎作用;肠系膜局部滴药引起大鼠血压15分钟内一过性升高,并使肠系膜微血管血流速度加快,毛细血管口径缩小。结论:滴通鼻炎水具有明显抗炎作用,能有效收缩小血管,加快血流速度,对全身血压没有持续影响。

Objective： To observe the effects of Ditong Rhinitis Water on the inflammation, the blood vessel contraction and the blood pressure of animals. Methods： Observing the antiinflammatory effects of the Ditong Rhinitis Water on the mice swellen auricle with dimethylbenzene, and observing the blood vessel contraction of mesenteric microcirculation and the systemic blood pressure by direct topical application of nasal drop to the mesentery of rats. Results： Ditong Rhinitis Water showed obviously antiinflammatory effects, meanwhde it momently elevated the blood pressure in 1-15 minutes, accelerated the blood stream of mesenteric micro blood vessel and contracted the capillary vessels. Conclusion： Ditong Rhinitis Water has distinctly antiinflammatory effects, effectually contracts the capillary vessels and accelerates the blood stream, and has not continually affects on the systemic blood pressure.