产后抑郁症发病危险因素研究

Study on risk factors of postpartum depression

目的探讨产后抑郁症发病的危险因素及预防。方法对200例(顺产100例、剖宫产100例)产妇进行问卷测查并检查血孕酮水平。结果顺产产后抑郁症的发生率低于剖宫产后抑郁症的发生率,差异有显著性(P<0.05)。抑郁组产后孕酮值低于无抑郁症组,差异有显著性(P<0.05)。抑郁组比无抑郁症组有较多不良的社会因素刺激(如生活压力大、家庭问题复杂)。遗传史与产后抑郁症无统计学关系。结论剖宫产后抑郁症的发生率比顺产高;产后血孕酮明显降低可能与抑郁症发生有关;不良的心理因素与不良社会刺激是产后抑郁的促进因素。

Objective To explore the risk factors for postpartum depression and the method for its prevention. Methods Two hundred partal women including 100 cases with vaginal delivery and 100 cases with cesarean section were randomly selected for survey with questionnaires. Results The incidence of postpartum depression in cases with vaginal delivery group was lower than that of cases with cesarean section group and its difference was statistically significant （ P 〈0.05 ）. Serum concentration of progesterone （P） was significantly lower in cases of depression group in comparison with those of non - depression group. More negative social factors, bad family economic condition and stress on family were more frequently seen in partal women of depression group than those of non - depression group. There was no statistically significant difference in heredofamilial history between these two groups. Conclusion The incidence of postpartum depression is higher in cases of cesarean section group in comparison with those of vaginal delivery group. Decrease in serum concentration of progesterone after delivery is the probable factor responsible for postpartum depression. Adverse psychological factors and negative social stress are main promoters for the occurrence of postpartum depression.