小气道阻力测定方法学的临床应用研究进展

Clinical practice and research progress in small airway resistance measure of resistance methodology

老年人由于增龄的机能衰退和呼吸生理的改变、长期生存于污染的大气环境、主动和被动吸烟均可造成不同程度的气道炎症及阻塞。小气道功能检查对评价老年人的呼吸功能尤其重要。小气道病变可能是慢性阻塞性肺疾病（chronic obstructive pulmonary disease，COPD）的早期和可逆阶段。因此，早期检查、及时预防和治疗小气道病变，对预防发展为不可逆阶段的COPD有重要的意义。

Because the senior citizen increases the age the function declines and the breath physiology changes, long-term survival in pollution atmospheric environment, initiative and passive smoking, may create the varying degree airway inflammation and blocking. Small airway functional measure to appraise senior breath function is especially important. Small airway pathological change possibly is the chronic obstructive pulmonary disease （COPD） early time and the reversible stage. Therefore, it has important meanings to conduct early inspection, prevent and treat small airway pathological change promptly, to stop the development into irreversible stage COPD.