紫外线照射充氧回输对肺心病患者血液流变学特性的影响

Study on hemorrheology of patients with cor pulmonale before and after autotransfusion of ultraviolet irradiated blood(AUVIB) therapy

紫外线照射充氧回输是肺心病常规治疗的基础上加用的辅助治疗，观察治疗前后的血液流变学改变及治疗效果，结果发现肺心病患者经该疗法辅助治疗后红细胞压积、纤维蛋白原含量、血浆比粘度及在切变率为１ｓ－１时的全血粘度较治疗前有明显改变（Ｐ＜００５），红细胞聚集指数及在切变率为２００ｓ－１和１００ｓ－１时的全血粘度与治疗前比较差异十分明显（Ｐ＜００１），而对照治疗组患者除血浆比粘度及红细胞聚集指数在治疗前后有明显改变（Ｐ＜００５）外，红细胞压积、纤维蛋白原含量、及在三种切变率下的全血粘度虽较治疗前有所改善，但与治疗前比较无统计学差异（Ｐ＞００５），由此可看出紫外线照射充氧回输辅助治疗能明显改善肺心病患者的血液流变学特性。

For further investigation the mechanism of AUVIB therapy, hemorrheologic changes were observed in 48 cases of patients with cor pulmonale Pathological changes of hemorrheological parameters were found in patients with cor pulmonale The blood viscosity coefficient, hematocrit and contents of fibrinogen were significantly higher than that of normal control group( P <0 01) The hematocrit ,contents of fibrinogen and ratio viscosity of plasma after AUVIB therapy were significantly lower than before AUVIB therapy( P <0 05) The red blood cell aggregation index and blood viscosity coefficient were decreased,which were of significant differences( P <0 01) as compared with those of before AUVIB therapy The viscosity ratio of plasma and red blood cell aggregation index of control therapy group were decreased after therapy, which were of significant differences( P < 0 05) as compared with those of before therapy Although the hematocrit,contents of fibrinogen and blood viscosity coefficient ratio viscosity were decreased after therapy,which were of no significant differences( P >0 05) as compared with those of before therapy The results showed that AUVIB therapy can improve the hemorrheological properties in patients with cor pulmonale