3Edaravone Acute Infarction Study Group.Effect of a novelf recradical cavenger,edaravone (MCI 186),on acute brain infarction.Randomized,placebo-controlled,double blind study at multicenters[J].Cerebrobasc Dis,2003,15(1-2):22.
2Amemiya S,Kamiya T,Nito C,et al.Anti-apoptotic and neuroprotective effects of edaravone following transient focal ischemia in rats[J].Eur J Pharmacol,2005,516(2):125-130.
3Marumo T,Schini-Kerth VB,Busse R.Vascular endothelial growth factor activates nuclear factor-kappaB and induces monocyte chemoattractant protein-1 in bovine retinal endothelial cells[J].Diabetes,1999,48(5):1131-1137.
4Zhang N,Komine-Kobayashi M,Tanaka R,et al.Edaravone rduces early accumulation of oxidative products and sequential inflammtory responses after transient focal ischemia in mice brain[J].Stroke,2005,36 (10):2220-2225.
5Wen J,Watanabe K,Ma M,et al.Edaravone inhibits JNK-cJun pathway and restores anti-oxidative defense after ischemia-reperfusion injury in aged rats[J].Biol Pharm Bull,2006,29 (4):713-718.
6Nakamura H,Uzura M,Uchida K,et al.Effects of edaravone on experimental brain injury in view of free radical reaction[J].Acts NeurochirSuppl,2003,86:309-311.
7Eiichi O.Effect of a novel free radical scavenger,Edaravone (MCI-186),on acute brain infarction[J].Cerebrovasc Dis,2003,15(3):222-229.