人工胶体对腹部手术后应激影响的比较

A Study of Artificial Colloid on Stress Reaction in Moderate Abdominal Operation

目的:比较明胶和羟乙基淀粉对中等腹部手术病人术后应激反应的影响。方法:选择中等腹部外科手术患者34例,随机分为羟乙基淀粉治疗组(18例)和明胶治疗组(16例)。术后连续3d内分别每日给予人工胶体500ml,比较两组患者术前、术后第1天、术后第3天的血糖水平、血清白蛋白浓度、C-反应蛋白浓度、血白细胞计数。结果:羟乙基淀粉组术后第1日的CRP比明胶组低,有统计学意义(P<0.05),且羟乙基淀粉组术后血糖变化与术前比较无统计学差异,P>0.05。结论:中分子羟乙基淀粉相对于琥珀酰明胶在减轻腹部手术后应激反应中起到一定的积极作用。

Objective. To compare the effect of hydroxyethyl starch and gelatin on stress reaction in moderate abdominal operation. Methods;Thirty-two patients undergoing moderate abdominal operation were randomly divided into two groups,hydroxyethyl starch group （n= 18） and gelatin group（n= 16）. Volume therapy with artificial colloid began since the end of the operation to postoperative clay three. Blood glucose , leucocyte count, albumin, C reactive protein were measured on the day before operation, postoperative day one and postoperative day three. The first postoperative passage of gas by anus was recorded. Results：Blood glucose in hydroxyethyl starch group didn＇t change much since the operation. CRP in hydroxyethyl starch group was lower than that in gelatin group at postoperative clay one. Conclusion; As compared with gelatin , hyclroxyethyl starch can reduce the stress reaction in moderate abdominal operation to a certain degree.