非小细胞肺癌个体化疗:由实验研究向临床过渡
摘要
标准化疗(standard chemotherapy)是目前非小细胞肺癌(NSCLC)最常接受的药物治疗方式,标准化疗方案有紫杉醇联合铂类、吉西他滨联合顺铂、异长春花碱联合顺铂。上述方案经大样本多中心前瞻性Ⅲ期临床试验,客观有效率只有21%。提高肺癌化疗的效果是临床迫切需要解决的难题。最近3~5年,抗肿瘤药物遗传学/基因组学的快速发展已经能够确定一些化疗药物疗效相关的关键基因。
出处
《中华病理学杂志》
CAS
CSCD
北大核心
2008年第5期344-345,共2页
Chinese Journal of Pathology
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