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子宫内膜异位症患者血清及腹腔液中单核细胞趋化蛋白-1水平变化的研究 被引量:1

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摘要 目的通过观察子宫内膜异位症(EM)患者血清及腹腔液中单核细胞趋化蛋白-1(MCP-1)的水平,探讨MCP-1在子宫内膜异位症发病中的作用。方法病例组选取EM患者45例,以酶联免疫吸附测定法(ELISA)定量检测EM患者血清及腹腔液中MCP-1的水平;对照组选取同期卵巢良性上皮肿瘤患者45例,比较两组患者血清及腹腔液中MCP-1的水平的差异。结果①EM早期组患者血清MCP-1水平[(231.6±44.9)ng/L]明显高于晚期组[(184.5±14.1)ng/L]及对照组[(159.1±8.9)],差异均有统计学意义(均P〈0.05)。②EM早期组患者腹腔液中MCP-1水平明显高于晚期组[(26.11±3.37)ng/L]及对照组[(9.32±5.24)ng/L],差异有统计学意义(均P〈0.05)。③EM患者血清及腹腔液中MCP-1水平明显高于对照组,差异有统计学意义(P〈0.05)。结论EM患者血清及腹腔液MCP.1水平明显升高,提示血清MCP-1水平在EM发病机制中起着一定作用。
出处 《中国综合临床》 北大核心 2008年第5期488-489,共2页 Clinical Medicine of China
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