期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

DD3基因在前列腺癌诊断中的研究进展 被引量：1

原文传递
导出
摘要 近年来，有关前列腺癌（Prostate cancer，Pca）诊断方法的研究成为了研究的热点，研究发现DD3是一种非编码RNA的基因，仅在Pea细胞中表达，而在其他正常组织和癌组织以及细胞系中均不表达，为Pea特异性基因之一，DD3的发现极大提高了Pea诊断的特异性与灵敏度。本文就DD3最新研究进展作一综述。
作者 朱金海(综述) 贾瑞鹏(审校)
机构地区 南京医科大学附属南京第一医院泌尿外科
出处 《国际泌尿系统杂志》 2008年第3期343-347,共5页 International Journal of Urology and Nephrology
关键词 前列腺肿瘤 基因
分类号 R737.25 [医药卫生—肿瘤]
  • 相关文献

参考文献13

  • 1Bussemakers M J, van Bokhoven A, Verhaegh GW, et al. DD3:a new prostate specific gene, highly over expressed in prostate cancer. J Cancer Res, 1999, 59 (23) : 5975 -5979.
  • 2Tinzl M,Marberger M, Horvath S, et al. DD3Pca3 RNA analysis in urine- a new perspective for detecting prostate cancer . J Eur Urol, 2004, 46 (2) : 182-186.
  • 3de Kok JB, Verhaegh GW, Roelofs RW, et al. DD3 ( PCA3 ) , a very sensitive and specific marker to detect prostate tumors. J Cancer Res, 2002, 62 (9) : 2695 - 2698.
  • 4Liang P, Pardee AB. Differential display. A general protocol. J Mol Biotechnol ,1998 ,10(3) :261-267.
  • 5Hessels D , Klein Gunnewiek JM , van Oort I , et al. DD3 ( PCA3 ) - based molecular urine analysis for the diagnosis of prostate cancer. J Eur Urol ,2003 ,44(1) :8 -16.
  • 6Fradet Y, Saad F, Ap rikian A, et al. uPM3, a new molecular urine test for the detection of prostate cancer. J Urology, 2004,64 ( 2 ) : 311 -315.
  • 7翁志梁,余凯远,毛晓露,陶志华,陈晓东,吴秀玲,胡元平,王思齐,李澄棣,陈占国.外周血差异显示编码3mRNA定量检测在前列腺癌患者诊断与治疗监测中的初步应用[J].中华医学杂志,2006,86(41):2911-2915. 被引量：9
  • 8Thelen P, Burfeind P, GrzmilM, et al. cDNA microarray analysis with amplified RNA after isolation of intact cellular RNA from neoplastic and non - neoplastic prostate tissue separated by laser microdissections. Int J Oncol, 2004, 24 (5) : 1085 - 1092.
  • 9Landers KA, Burger MJ, Tebay MA, et al. Use of multiple biomarkers for a molecular diagnosis of prostate cancer. Int J Cancer, 2005, 114(6) :950 -956.
  • 10Popa I, Fradet Y, Beaudry G, et al. Identification of PCA3 ( DD3 ) in prostatic carcinoma by in situ hybridization. Mod Pathol. 2007 20 (11) :1121 - 1127.

二级参考文献19

  • 1陈占国,陶志华,陈晓东,李澄棣,李湘斌,杨建荣,温秀姝,林晓梅,朱燕英.前列腺癌患者外周血DD3 mRNA的检测及临床意义[J].中华检验医学杂志,2005,28(5):489-491. 被引量：11
  • 2那彦群,李鸣.重视前列腺癌诊治规范化研究[J].中华医学杂志,2005,85(45):3169-3169. 被引量：21
  • 3朱培元,洪萍,黄宇烽.前列腺特异性抗原前体用于前列腺癌早期诊断[J].中华男科学杂志,2005,11(12):944-946. 被引量：2
  • 4Bussemakers MJ,van Bokhoven A,Verhaegh GW,et al.DD3:a new prostate-specific gene,highly overexpressed in prostate cancer.Cancer Res,1999,59:5975-5979.
  • 5de Kok JB,Verhaegh GW,Roelofs RW,et al.DD3 (PCA3),a very sensitive and specific marker to detect prostate tumors.Cancer Res,2002,62:2695-2698.
  • 6Hessels D,Klein Gunnewiek JM,van Oort I,et al.DD3 (PCA3)-based molecular urine analysis for the diagnosis of prostate cancer.Eur Urol,2003,44:8-16.
  • 7Tinzl M,Marberger M,Horvath S,et al.DD3PCA3 RNA analysis in urine-a new perspective for detecting prostate cancer.Eur Urol,2004,46:182-187.
  • 8Gandini O,Luci L,Stigliano A,et al.Is DD3 a new prostatespecific gene ? Anticancer Res,2003,23:305-308.
  • 9Thompson IM,Pauler DK,Goodman PJ,et al.Prevalence of prostate cancer among men with a prostate-specific antigen level ＜or = 4.0 ng per milliliter.N Engl J Med,2004,350:2239-2246.
  • 10Norberg M,Egevad L,Holmberg L,et al.The sextant protocol for ultrasound-guided core biopsies of the prostate underestimates the presence of cancer.Urology,1997,50:562-566.

共引文献21

同被引文献35

  • 1Siegel R, Ward E, Brawley O, et al. Cancer statistics, 2011 : the impact of eliminating socioeconomic and racial disparities on prema- ture cancer deaths. CA Cancer J Clin,2011,61 (g) : 212 -236.
  • 2Etzioni R, Gulati R, Falcon S, et al. Impact of PSA screening on the incidence of advanced stage prostate cancer in the United States : a surveillance modeling approach. Med Decis Making,2008,28(3) : 323 - 331.
  • 3Klein EA. What new in prostate cancer screening and prevention? Cleve Clin J Med, 2009,76 ( 8 ) :439 - 445.
  • 4Jayadevappa R, Chhatre S, Weiner M, et al. Medical care cost of patients with prostate cancer. Urol Oncol,2005,23(3) : 155 -162.
  • 5Guh DP, Zhang W, Bansback N, et al. The incidence of co - mor- bidities related to obesity and overweight: a systematic review and meta - analysis. BMC Public Health, 2009,9 : 88 - 108.
  • 6Stamatiou K, Skolarikos A. Rural residence and prostate cancer screening with prostate -specific antigen. Rural Remote Health, 2009,9(2) : 1227.
  • 7Hamashima C, Nakayama T, Sagawa M, et al. The Japanese guide- line for prostate cancer screening. Jpn J Clin Oncol, 2009,39 ( 6 ) : 339 -351.
  • 8Schroder FH, Hugosson J, Roobol M J, et al. Screening and prostate - cancer mortality in a randomized European study. N Engl J Med, 2009,360( 13 ) : 1320 - 1328.
  • 9Hugosson J, Carlsson S, Aus G, et al. Mortality results from the Goteborg randomised population - based prostate - cancer screening trial. Lancet Oncol,2010,11 (8) : 725 - 732.
  • 10Draisma G, Etzioni R, Tsodikov A, et al. Lead time and overdiag- nosis in prostate - specific antigen screening: importance of methods and context. J Natl Cancer Inst,2009,101 (6) : 374 - 383.

引证文献1

国际泌尿系统杂志
2008年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部