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CTGF的研究进展及在慢性肾脏疾病中的新认识

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摘要 CTGF作为许多因子的EMT及致纤维化作用的下游共同介质,越来越引起研究者的关注,它为控制纤维化提供了一个新的治疗靶点。通过对CTGF基因表达调节,受体结合和信号转导途径的进一步研究,将有助于靶向CTGF系统的抗纤维化治疗以及开发有效的治疗脏器纤维化的药物,为今后防治纤维化疾病带来新的希望。
出处 《国际泌尿系统杂志》 2008年第3期425-428,共4页 International Journal of Urology and Nephrology
基金 本课题受国家自然基金资助:3047173
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