近红外光谱无创伤血糖浓度测量的内部干扰因素分析

Analyses on Internal Interferer Factors in Noninvasive Measurement of Blood Glucose Concentration with Near-infrared Spectroscopy

生理变化是血糖无创伤测量过程中重要的干扰因素,而且不受人为控制。分析了温度变化对于组织的近红外吸收和散射特性的影响机制、特点和定量关系,以及对比研究了体内非糖成分变化与葡萄糖变化对组织光学特性的影响比例和速度。这些内部干扰因素的研究有助于探索新的光谱信号采集和处理方法,从而促进血糖无创伤测量的实现。

Physiological variation are one of important interruption factors in noninvasive measurement of blood glucose concentration,and they are out of artificial control.Influencing mechanism,characteristic and quantitative relation of temperature change on absorbance and scattering properties of near infrared light in tissue are analyzed.And comparisons about the ratio and speed of glucose and other components influencing on tissue optical properties are carried out.All these investigations about internal interruption factors are expected to help find new methods of signal acquiring and processing,and further accelerate the realization of noninvasive measurement of blood glucose.