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环氧化酶-2及其抑制剂与头颈肿瘤细胞增殖和凋亡 被引量：1

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摘要 有关环氧化酶-2（cyclooxygenase-2，COX-2）及其抑制剂在肿瘤中的作用机制研究已经相当广泛，对于其在头颈鳞状细胞癌中的研究也越来越深入，目前认为COX-2参与肿瘤发生的机制可能与多个环节有关。本文主要综述了COX-2及其抑制剂在头颈部鳞状细胞癌细胞增殖和凋亡中的作用机制，并对COX-2抑制剂抗肿瘤依赖和非依赖COX-2途径进行探讨。
作者 谌敏峰 覃纲 余玲 梁传余 王力红 刘世喜
机构地区 四川大学华西医院耳鼻咽喉头颈外科 泸州医学院附属医院耳鼻咽喉头颈外科 泸州医学院附属医院眼科
出处 《国际耳鼻咽喉头颈外科杂志》 2008年第3期156-159,共4页 International Journal of Otolaryngology-Head and Neck Surgery
基金 四川省应用基础研究项目（05JY029-10L4）
关键词 环氧化酶-2 癌 鳞状细胞 细胞增殖 细胞凋亡 Cyclooxygenase-2 Carcinoma, SquamousCell CellProliferation Apoptosis
分类号 R285.5 [医药卫生—中药学]
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参考文献20

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二级参考文献33

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共引文献21

同被引文献29

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国际耳鼻咽喉头颈外科杂志
2008年 第3期

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