^(18)F-FDG PET显像和CT平扫对原发和复发鼻咽癌诊断价值的比较

The different diagnostic value of ^(18)F-FDG PET imaging and CT scan in primary and recurrent nasopharyngeal carcinoma

目的探讨18F-FDG PET/CT显像中的PET和CT对原发和复发鼻咽癌诊断价值的差别。方法对48例均经病理确诊鼻咽腔内有癌组织存在的鼻咽癌患者进行18F-FDG PET/CT显像,并按治疗经过分为原发组(A组)和复发组(B组),分别统计、比较PET和CT对A、B两组病例的检出率。结果A组的PET和CT的检出率分别是94.74%(36/38)和84.21%(32/38)(P>0.05,χ2=1.30);B组的PET和CT的检出率分别是10%(1/10)和30%(3/10)(P>0.05,χ2=0.83)。PET检查A、B组的检出率分别是94.74%(36/38)和10%(1/10),差异有统计学意义(P<0.01,χ2=27.56),CT检查A、B两组的检出率分别是84.21%(32/38)和30%(3/10),差异有统计学意义(P<0.01,χ2=9.20)。结论18F-FDG PET和CT对鼻咽癌病灶的检出率有高度的一致性,18F-FDG PET/CT诊断原发鼻咽癌比复发鼻咽癌更敏感。

Objective To study the different diagnostic value between ^18F-FDG PET imaging and CT scan in primary and reeument nasopharyngeal carcinoma （NPC）. Methods 48 patients with NPC underwent wholebody ^18F-FDG- PET/CT imaging,and were divided into two groups according to primary or recurrent. Group A included primary NPC（38 eases） and group B was reeurrent NPC（ 10 eases）. Compared the positive rates of PET and CT in the two groups separately. Results The positive rates of PET and CT in group A was 94.74% （36/38） and 84.21% （ 32/38）, no significant differenee was found（ P 〉 0. 05, X^2 = 1.30 ）, and in group B, PET was 10% （ 1/10 ）, CT was 30% （ 3/10）, also no significant difference（ P 〉 0.05, X^2 = 0.83）. The positive rates of PET in group A and B were 94.74% （36/38） and 10% （ 1/10）, showed the significant difference （P 〈0.01 X^2 =27.56）. The positive rates of CT in group A and B were 84.21% （32/38） and 30% （3/10）, also showed the significant difference （P 〈 0.01, X^2 = 9.20）. Conclusion The positive rate of ^18F-FDG PET is coincident with that of CT in NPC. ^18F-FDG PET/CT is more sensitive in primany NPC than in the recurrent.