期刊文献+

甘精胰岛素联合口服降糖药治疗糖尿病的疗效

下载PDF
导出
摘要 目的:探讨门诊2型糖尿病患者在口服降糖药血糖降低未达标时联合应用甘精胰岛素的疗效。方法:选择30例门诊2型糖尿病患者,在使用两种口服降糖药治疗,血糖降低仍未达标时联合应用甘精胰岛素,疗程为9个月,观察治疗前后糖化血红蛋白(HbAlc)的变化,并且统计低血糖症的发生例数。结果:治疗9个月后HbAlc较治疗前明显降低(P<0.001),无严重低血糖症出现。结论:门诊2型糖尿病患者在使用2种口服降糖药治疗血糖降低未达标时联合甘精胰岛素,可有效地降低HbAlc。
出处 《中国药师》 CAS 2008年第5期565-566,共2页 China Pharmacist
  • 相关文献

参考文献6

二级参考文献16

  • 1傅祖植.磺脲类口服降糖药继发失效及其处理[J].中国糖尿病杂志,1994,2(1):44-45. 被引量:33
  • 2吴晨光.诺和灵N治疗2型糖尿病磺脲类药物继发性失效临床观察[J].江苏大学学报(医学版),2004,14(30):216-217. 被引量:6
  • 3Muller G,Wied S.The sulfonylurea drug,glimepiride,stimulates glucose transport,glucose transporter translocation,and dephosphorylation in insulin-resistant rat adipocyt in vitro[J].Diabetes,1993,42 (12):1852 -1867.
  • 4The Diabetes Control and Complication Trail Research Group.The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus[J].N Engl J Med,1993,329(14):977 -986.
  • 5UK Prospective Diabetes Study (UKPDS) Group.Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes[J].Lancet,1998,352(9131):837-853.
  • 6Riddle MC.Timely addition of insulin to oral therapy for type 2 diabetes[J].Diabetes Care,2002,25 (2):395 -396.
  • 7Bolli GB,Owens DR.Insulin glargine[J].Lancet,2000,356(9228):443-445.
  • 8Rosenstock J,Schwartz SL,Clark CM Jr,et al.Basal insulin therapy in type 2 diabetes:28-week comparison of insulin glargine(HOE901) and NPH insulin[J].Diabetes Care,2001,24 (4):631-636.
  • 9Brun E, Zoppini G, Zamboni C, et al. Glucose instability is associated with a high level of circulating p-selectin. Diabetes Care, 2001,24(9) :1685.
  • 10Muggeo M, Zoppini G, Bonora E, et al. Fasting plasma glucose variability predicts 10-year survival of type 2 diabetic patients: the Verona Diabetes Study. Diabetes Care, 2000,23(1) :45-50.

共引文献492

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部