摘要
目的:了解药品不良反应(ADR)的发生情况以及给患者造成的危害。方法:对我中心2006年评价后的366例ADR报告进行分类统计和分析。结果:涉及ADR的药物共有120个品种,其中,抗感染药物居首位,其次为循环系统(心脑血管)药物。ADR中合并用药72例(19.7%),97%是静脉给药。主要的ADR类型为皮肤损害,其次是心血管系统损害、神经系统损害、胃肠道系统、发热、寒战等全身症状。重度ADR有22例(占6.0%),其中死亡4例(1.1%)。结论:ADR不容忽视,应加强监测。
Objective： To analyze on 366 cases of adverse drug reaction reports. Method： Three hundreds and sixty-six cases of ADR reports from ADR monitoring center were collected and analyzed in 2006. Result： Among the reported cases, 120 kinds of drugs related to ADR,the first place was anti-infective drugs ,with circulatory system drugs followed. Seventy-two cases （19.7% ） were combined usage of drugs, intravenously administration with drugs were 97.0%. Major clinical manifestation involved skin damage, cardiovascular system, nervous system, gastro-intestinal tract reaction, drug fever, and chilliness followed etc. Twenty-two cases were serious ADR （6.0%） ,among which 4 died （1.1%）. Conclusion： It must strengthen monitoring and never neglect for ADR.
出处
《中国药师》
CAS
2008年第5期567-568,共2页
China Pharmacist
