耳针治疗围绝经期综合征34例临床观察

Clinical Observation on the Auricular Acupuncture for Perimenopause Syndrome of 34 Cases

目的比较耳针与激素替代疗法治疗围绝经期综合征的临床疗效,初探耳针疗法的作用机理。方法将68例围绝经期综合征患者随机分为耳针组(34例)和激素组(34例),耳针组电针耳穴内分泌、卵巢、子宫等,激素组口服替勃龙(7-甲异炔诺酮),共治疗1个月。治疗前后分别进行临床症状评分(Kupperman评分)及血清雌二醇(E2)、促卵泡生成素(FSH)、促黄体生成素(LH)含量测定。结果两组治疗后的Kupperman评分均较治疗前显著降低(P<0.01)。两组治疗后E2水平较治疗前均明显升高(P<0.05或P<0.01),FSH和LH均下降(P<0.01);治疗后耳针组E2水平较对照组偏低(P<0.05)。两组临床有效率差异无统计学意义(P>0.05)。结论耳针疗法可有效缓解围绝经期综合征,并在一定程度上改善围绝经期女性的生殖内分泌功能。

Objective To compare the therapeutic effect of auricular acupuncture with that of hormone substitution on perimenopause syndrome patients to study the mechanism of auricular therapy. Methods Totally 68 female cases were randomized into the auricular acupuncture group and hormone group, 34 cases in each. The auricular acupuncture group was given electro-acupuncture on Neifenmi（CD18）,Ovarium,and Uterus;and the hormone group was given Tibolone. Before and after treatment, record Kupperman score and determine serum estradiol （E2）, follicle-stimulating hormone （FSH） and luteotropic hormone （LH） respectively. Results After treatment, the Kupperman scores of both groups were decreased, the level of E2 increased obviously, FSH and LH decreased ,the difference was significant （P〈0. 05 ,P〈0.01 ）. The level of E2 in the auricular acupuncture group after treatment was lower than that of hormone group （P〈0.05）. The therapeutic effect of auricular acupuncture group and hormone group was not significantly different （P〈0. 05）. Conclusion The auricular therapy can effectively relieve the perimenopause syndrome and improve the reproductive endocrine function of perimenopause females.