期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

γ-氨基丁酸类抗癫癎药物对眼部功能的影响

GABAergic Antiepileptic Drugs on Ocular Performance
原文传递
导出
摘要 γ-氨基丁酸(GABA)类抗癫癎药物在治疗量内对视觉功能影响的不良反应与药物的治疗作用机制有关,本综述探讨GABA类抗癫癎药对视觉功能的影响及可能的发生机制。 GABAergic antiepileptic drugs are associated with some specific visual problems that may be related to the mechanistic properties of the drug in therapeutic dose. The following review outlines the visual disturbances associated with some of the most commonly prescribed anticonvulsants. For each drug, the ocular site of potential damage and the likely mechanism responsible for the adverse visual effects is described.
作者 王庆平 叶纹
机构地区 复旦大学附属华山医院眼科
出处 《中国临床神经科学》 2008年第3期332-336,共5页 Chinese Journal of Clinical Neurosciences
关键词 Γ-氨基丁酸 抗癫痫药物 视野 色觉 对比敏感度 γ-aminobutyric acid（GABA） antiepileptic drugs visual fields color perception contrast sensitivity
分类号 R77 [医药卫生—眼科] R742.1 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献36

  • 1Schmidt M. GABA(C) receptors in retina and brain[J]. Results Probl Cell Differ, 2008, 44:49-67.
  • 2Casini G, Rickman DW, Brecha NC. Expression of the gammaaminobutyric acid (GABA) plasma membrane transporter-1 in monkey and human retina[J]. Invest Ophthalmol Vis Sci, 2006, 47:1682-1690.
  • 3Yang XL. Characterization of receptors for glutamate and GABA in retinal neurons[J]. Prog Neurobiol, 2004, 73:127-150.
  • 4Hilton EJ, Hosking SL, Betts T. The effect of antiepileptic drugs on visual performance[J]. Seizure, 2004, 13:113-128.
  • 5Daneshvar H, Racette L, Coupland SG, et al. Symptomatic and asymptomatic visual loss in patients taking vigabatrin[J]. Ophthalmology, 1999, 106:1792-1798.
  • 6Wild JM, Ahn HS, Baulac M, et al. Vigabatrin and epilepsy: lessons learned[J]. Epilepsia, 2007, 48:1318-1327.
  • 7Conway M, Cubbidge RP, Hosking SL. Visual field severity indices demonstrate dose-dependent visual loss from vigabatrin therapy [J]. Epilepsia, 2008, 49:108-116.
  • 8Kjellstrom U, Lovestam-Adrian M, Andreasson S, et al. Full-field ERG and visual fields in patients 5 years after discontinuing vigabatrin therapy[J]. Doc Ophthalmol, 2008[Epub ahead of print].
  • 9Pojda-Wilczek D, Emich-Widera E, Herba E, et al. The function of eye and vision system in children and youth treated with vigabatrinour own experiences[J]. Klin Oczna, 2005, 107:654-657.
  • 10Mecarelli O, Rinalduzzi S, Accornero N. Changes in color vision after a single dose of vigabatrin or carbamazepine in healthy volunteers[J]. Clin Neuropharmacol, 2001, 24:23-26.
中国临床神经科学
2008年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部