中青年短暂性脑缺血发作患者临床特征分析

The profile of transient ischemic attacks in younger patients

目的总结分析中青年短暂性脑缺血发作患者的临床特征。方法对1999年至2002年北京世纪坛医院确诊的短暂性脑缺血发作75例中青年(≤45岁)患者及90例老年(≥60岁)患者的发病危险因素、病史、临床表现以及实验室检查资料进行比较分析。结果肥胖、高脂血症、睡眠障碍及血管病家族史在中青年组发生率高,高血压、缺血性心脏病、长期吸烟史、周围血管病以及颈动脉狭窄症在老年组发生率高,糖尿病及高尿酸血症在两组均占较高比例。椎基底动脉系短暂性脑缺血发作发生率中青年组低于老年组(P<0.05)。结论中青年短暂性脑缺血发作者与老年患者比较有不同的发病危险因素和临床特征。其危险因素分析显示与不良生活方式有关,应给予早期干预。

Objective To evaluate the profile of transient ischemic attacks in younger patients compared with older patients effectively. Methods We study 75 younger patients （ ≤45 years） compared with 90 older patients （≥65 years）. History of presenting transient ischemic attacks, etiology, clinical feature and lab investigation were compared on the basis of the above age groups. Results Overweight, hypereholesterolemia,insomnia and vascular disease family history being more common in the younger group and Hypertension, ischemic heart disease, long - term history of smoking being more common in the elder group. Diabetes and high serum uric acid occurred high frequently in both groups. Conclusion A significant correlation existed between etiologies contribution and adverse life custom, the early management should be take up to prevent TIA occurrence.