某高校学生乙型肝炎血清检测结果及影响因素

Analysis on Hepatitis B Virus Infection and Influencing Factor of New and Graduation Students from One University

目的了解河南某高校2004级在校学生乙型肝炎病毒感染状况及影响因素。方法采用酶联免疫吸附试验(ELISA)法检测2004级学生入学与毕业时血清乙肝五项指标,并以问卷调查的方式了解影响学生乙型肝炎血清指标的因素。结果该级学生入学与毕业时HBsAg阳性率分别为9.87%和10.61%,差别无统计学意义;乙肝五项的构成模式由入学的6种变为毕业时的8种;不同性别、乙肝感染家族史、输血史、疫苗接种史的学生,入学和毕业时HBsAg阳性率间差别有统计学意义(P<0.05);不同生源地的学生入学时HBsAg阳性率间差别有统计学意义(P<0.05),而毕业时差别无统计学意义(P>0.05)。结论大学生在校期间要重视对乙肝的预防;学校应加强对学生的健康教育,制定并实施相应的预防措施。

Objective To understand the situation of hepatitis B virus infection among the students in university in order to make effective measure for its propagation and epidemic. Methods To test HbsAg, HBsAb , HBeAg , HBeAb and HBcAb by enzyme linked immunoabsorbent assay （ELISA） for each students , and understand the effective factor of HbsAg carrier from the every students by questionaire. Results The total HBsAg positive rate was 9.87% and 10.61% respectively of the new and graduation students;The five makers about HBV of HBsAg positive carrier became from six kinds by new students to eight kinds by graduation students ; The HBV of HBsAg positive carrier has significance of difference in the different gender, HBV - infected history, blood transfusion his- tory and HBV vaccination history（ P 〈 0.05） about the new and graduation students,but the different source place is not about graduation students （ P 〉 0.05）. Conclusion The students must notice HBV precaution during they had been in university. Health education on HBV and prevention program should be implemented to prevent infection.