甲状腺结节钙化的意义及临床分析

The significance and the clinical analysis of calcification in thyroid node

目的探讨甲状腺结节钙化对诊断甲状腺癌的意义。方法对比107例甲状腺手术患者的术前超声、术中所见，结合病理结果进行分析。结果所有患者术前均行超声检查，钙化检出率为27．1％（29／107）。良性结节钙化发生率为17．2％（15／87），其中微钙化发生率8．0％（7／87）；甲状腺癌的钙化发生率为70．0％（14／20），其中微钙化发生率50．0％（10／20）。两者钙化发生率、微钙化发生率比较差异均有统计学意义（P〈0．01）。良性结节的单结节钙化发生率33．3％（5／15），甲状腺癌的单结节钙化发生率57．1％（8／14），两者比较差异有统计学意义（P〈0．01）。结论甲状腺癌结节出现钙化的几率高，特别是单结节的微钙化对甲状腺癌的诊断意义重大。

Objective To investigate the significance of calcification in thyroid node for diagnosis of thyroid carcinoma. Method Retrospective analysis of 107 thyroid nodules＇ pre-operative ultrasonic and postoperative pathologic results. Results Total ultrasonic thyroid calcification ratio was 27.1% （29/107）, which in benign samples was lower than that in malignant samples（ 17.2% vs 70.0% ,P 〈 0.01 ）. Micro-calcification ratio in benign samples was lower than that in malignant samples （8.0% vs 50.0% ,P 〈 0.01）. Conclusion The ratio of thyroid carcinoma with calcification is higher,so the detection of thyroid carcinoma , especially micro-single-calcification should be significant.