期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

脂联素与冠心病及其危险因素关系的研究进展 被引量：7

下载PDF
导出
摘要 脂联素是脂肪细胞分泌的脂肪因子之一,与代谢综合征的各组分关系密切,成为近来研究的热点。本文就脂联素与冠心病及其危险因素关系的最新研究进展进行综述。
作者 徐昶 周强 马业新
机构地区 华中科技大学同济医学院附属同济医院心内科
出处 《中国动脉硬化杂志》 CAS CSCD 2008年第2期158-160,共3页 Chinese Journal of Arteriosclerosis
关键词 内科学 脂联素 冠心病 血脂异常 胰岛素抵抗 糖尿病 高血压
分类号 R5 [医药卫生—内科学]
  • 相关文献

参考文献22

  • 1Schever PE, williams S, Fogliano M, Baldini G, Lodish HF. A novel serum protein similar to Clq, produced exclusively in adipocytes [J]. ] Biol Chem,1995, 270 (45): 26746-749.
  • 2Aftra Y, Kihara S, Ouchi N, Takshashi M, Maeda K, Miyagawa J, et al. Paradoxical decrease of an adipose-specific protein,adiponectin,inobesity[J].Biochem Biophys Res Commun. 1999, 257 (1): 79-83.
  • 3Maeda K,Okubo K,Shimomura I,Funahashi T,Matsuzawa Y,Matsubara K.cDNA cloning and expression of an novel adipose -specific collagen-like factor apM1 (sdipose most abundant gene transcript1)[J].Biochem Biophys Res Commun.1996,221(2):286-289.
  • 4Hara K, Boutin P, Mini Y, Tobe K, Dina C, Yasuda K, et al. Genetic variation in the gene encoding adiponectin is associated with an incressed risk of type 2 diabetes in the Japanese Population [ J]. Diabetes, 2902, 51 (2) : 536-540.
  • 5Aso Y,Yamamoto R,Wakabayashi S,Uchida T,Taksyanagi K,Takebayashi K,et al.Comparison of serum high-molecular weight(HMW)adiponectin with total adiponectin concentrations in type 2diabetic patients with coronary artery disease using a novel erzyme-linked immunosorbent assay to detect HMW adiponectin [J].Diabetes,2006,55(7):1954-960.
  • 6Shimabukuro M,Higa N,Asshi T,Oshiro Y,Takasu N,Tagawa T,et al.Hypoadiponectinemia is closely linked to endothelial dysfunction in man[J].J Clin Endocrinol Metab,2003,88(7):3236-240.
  • 7Okamoto Y,Kinars S,Ouchi N,Nishida M,Arita Y,Kumsda M,et al.Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice[J].Girculation,2002,106(22):2767-770.
  • 8刘岩,邹大进,李慧,陈月,丁继军,郑兴,郭鹏飞.低脂联素血症是冠状动脉粥样硬化严重程度的重要标志[J].中华内分泌代谢杂志,2005,21(1):5-8. 被引量：111
  • 9Nakamura y,Shimada K,Fukuda D,Shimada Y,Ehara S,Hirose M,et al.Implications of plasma concentrations of adiponectin in patients with coronary artery disease [J].Heart,2004,90(5):528-533.
  • 10刘叶,于晓玲.不同类型冠心病患者血清脂联素水平及冠心病危险因素的变化[J].中国心血管病研究,2006,4(4):287-289. 被引量：19

二级参考文献31

  • 1刘军,陈影,刘芳,姚庆姑,许火根,澎名淑,郭瑜琳,陈钦达.2型糖尿病家系非糖尿病一级亲属脂联素水平与胰岛素抵抗和动脉粥样硬化相关性研究[J].中华内分泌代谢杂志,2004,20(3):215-216. 被引量：30
  • 2李光伟,Step.,L.检测人群胰岛素敏感性的一项新指数[J].中华内科杂志,1993,32(10):656-660. 被引量：2125
  • 3[1]Scherer PE,Williams S,Fogliano M,et al.A novel serum protein similar to Clq,produced exclusively in adipocytes.J Biol Chem,1995,270:26746-26749.
  • 4[2]Fruebis J,Tsao TS,Javorschi S,et al.Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice.ProcNatl Acad Sci USA,2001,98:2005-2010.
  • 5[3]Tomas E,Tsao TS,Saha AK,et al.Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain:acety1-CoA carboxylase inhibition and AMP-activated protein kinase activation.Proc Natl Acad Sci USA,2002,99:16309-16313.
  • 6[4]Yamauchi T,Kamon J,Mizokoshi Y,et al.Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMPactivated protein kinase.Nat Med,2002,8:1258-1259.
  • 7[5]Ouchi N,Kihara S,Arita Y,et al.Adipocyte derived plasma protein adiponectin,suppresses lipid accumulation and class A scavenger receptor expression in human monocyte derived macrophages.Circu-lating,2001,103:1057-1063.
  • 8[7]Poulter N.Coronary heart diaease is a mulfifactorial disease.Am J Hypertens,1999,12:S92-S95.
  • 9[8]Philip KG,Gregorio D,Lu T,et al.Adiponectin expression from human adipose tissue:relation to obesity,insulin resistance and tumour necrosis-αexpression.Diabetes,2003,52:1779-1785.
  • 10Okamoto Y, Arita Y, Nishida M, et al. An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls. Horm Metab Res, 2000,32:47-50.

共引文献128

同被引文献55

  • 1许文灿,林建才,詹勇平,林少达,林丹,陈永松.老年冠心病胰岛素抵抗与脂代谢紊乱[J].中国基层医药,2004,11(11):1297-1298. 被引量：9
  • 2各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量：33020
  • 3王义成,袁桂莉,赵九安.冠心病患者颈动脉粥样硬化与血管内皮舒张功能的临床研究[J].河北北方学院学报（医学版）,2007,24(1):9-11. 被引量：8
  • 4Bulcao C, Ferreira SR, Giuffrida FM, et al. The new adipose tissue and adipocytokines [J]. Cttrr Diabetes Rev, 2006, 2 ( 1 ) : 19-28.
  • 5Fukuhara A, Matsuda M, Nishizawa M, et al. Visfatin: a protein secreted by visceral fat that mimics the effects of insulin [ J ]. Science, 2005, 307 (5 708) : 426-430.
  • 6Malyszko J, Malyszko JS. Pawlak K, el al. Visfatin and apelin, new adipocytokines, and their relation to endothelial function in patients with chronic renal failure [ J ]. Adv Med Sci, 2008,53(1) : 32-36.
  • 7Takebayashi K, Suetsugu M, Wakabayashi S, et al. Association between plasma visfatin and vascular endothelial function in patients with type 2 diabetes menitus [ J]. Metabolism, 2007, 56 (4): 451-458.
  • 8Kim SR, Bae YH, Bae SK, et al. Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-kappaB activation in endothelial cells [ J ]. Biochim Biopt, ys Acta, 2008, 1 783 (5) : 886-895.
  • 9Adya R, Tan BK, Punn A, et al.Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced anglogenesis[J]. Cardiovoac Res, 2008, 78 (2) : 356-365.
  • 10Dalai TB, Yndestad A, Skjelland M, et al. Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: possible role in inflammation and plaque destabilization [J]. Circulation, 2007, 115 (8) : 972-980.

引证文献7

二级引证文献37

中国动脉硬化杂志
2008年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部