2Stewart BF,Siacovick D,Lind BK,et la.Clinical factors associated with calcific aortic valve disease [J].J Am Coll Cardiol, 1997, 29 (3) :630-634.
3Rajamannam MN,Subramaniam M,Rickard D,et al.Human aortic valve calcification is associated with an osteoblast phenotype[J].Circulation,2003,107(17):2182-184. 2003, 107 (17):2 182-184.
4Otto CM,Kuusisto J,Reichenbach DD,et al.Characteristics of the early lesion of 'degenerative'valvular aortic stenosis:histological and immunohistochemical studiea[J].Circulation,1994,94(:2):844-853.
6O'Brien KD,Pathogenesis of calcific aortic valve disease:a disease process come of age(and a good deal more)[J].Arteroscler Thromb Vasc Biol,2006,26(8):1721-728.
7Allison MA, Cheung P, Criqui MH, et al. Mitral and sonic annular calcification me hishly associated with systemic calcified atherosclerosis [ J].Circulation, 2006, 113 (6) :861-866.
8Garg V,Muth AN,Ransom JF,et al.Mutations in NOTCH 1 cause sortic valve disease[J].Nature,2005,437(7056):270.
9Otto CM, Lind BK, Kitzman DW, et al. Association of aortic-vslve sclerosis with cardiovascular mortality and morbidity in the elderly [ J ], N Engl J Med, 1999, 341 (3) : 142-147.
10Adler Y,Herz 1,Varuri M,et al.Mitral annular calcium detected by transthoracic echocardiography is a marker for high prevalence and severity of coronary artery disease in patients undergoing coronary angiography[J].Am J Cordiol, 1998, 82 (10):1183-186.
2[1]Demer LL.A skeleton in the atherosclerosis closet.Circulation,1995,92 (8):2029 ~ 2032.
3[2]Honye J,Mahon DJ,Jain A,et al.Morphological effects of coronary balloon angioplasty in vivo assessed by intravascular ultrasound imaging.Circulation,1992,85(3):1012~1025.
4[3]Agatston AS,Janowitz WR,Hildner FJ,et al.Quantification of coronary artery calcium using ultrafast computed tomography.J Am Coll Cardiol,1990,15(4) :827~832.
5[4]Doherty TM,Detrano RC.Coronary arterial calcification as an active process:a new perspective on an old problem.Calcif Tissue Iht,1994,54(3) :224~230.
6[5]Ikeda T,Shirasawa T,Esaki Y,et al.Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta.J Clin Invest,1993,92(6) :2814~2820.
7[6]Oldberg A,Franzen A,Heinegard D.Cloning and sequence analysis of rat bone sialoprotein (osteopontin)cDNA reveals an Arg-Gly-Asp cell-binding sequence.Proc Natl Acad Sci U S A,1986,83(23):8819 ~8823.
8[7]Termine JD,K leinman HK,Whitson SW,et al.Osteonectin,a bone-specific protein linking mineral to collagen.Cell,1981,26( 1 ) :99~ 105.
9[8]Hirota S,Imalita M,Kohri K,et al.Expression of osteopontin messenger RNA by macrophages in atherosclerotic plaques.A possible association with calcification.Am J Pathol,1993,143 (4):1003 ~1008.
10[9]Gadeau AP,Chaulet H,Daret D,et al.Time course of osteopontin,osteocalcin,and osteonectin accumulation and calcification after acute vessel wall injury.J Histochem Cytochem,2001,49 ( 1 ):79~ 86.
9Otto CM, Kuusisto J, Reichenbach DD, et al. Charac-terization of the early lesion of degenerative' valvu- laraortic stenosis. Histological and immunohistochemical studies [ J ]. Circulation, 1994, 90(2): 844-853.
10Rosenhek R, Binder T, Porenta G, et al. Predictors of outcomes in severe, asymptomatic aortic stenosis [ J ]. N Engl J Med,2000,33(9) :611-617.