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六味安消胶囊治疗原发性胆汁反流性胃炎的疗效观察 被引量:2

Clinical effect of liuweianxiao capsule in primary bile reflux gastritis
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摘要 目的:探讨六味安消胶囊治疗原发性胆汁反流性胃炎的疗效、安全性及耐受性。方法:62例原发性胆汁反流性胃炎患者随机分为两组,治疗组32例和对照组30例,治疗组给予六味安消胶囊3粒/次,3次/天;对照组给予枸橼酸莫沙比利5 mg/次,3次/天;疗程均为4周。分别于治疗前后观察两组的症状变化,比较两组的临床疗效及不良反应。结果:两组治疗后均可明显改善患者上腹疼痛、烧心、腹胀、嗳气、恶心或呕吐胆汁等症状,治疗组总有效率90.62%;对照组为93.33%。两组治疗后临床症状的总有效率差异无显著性(P>0.05)。两组患者治疗后均未出现明显不良反应。结论:六味安消胶囊是治疗原发性胆汁反流性胃炎安全、有效的药物。 Objective:To investigate the clinical effect,safety and tolerability of liuweianxiao capsule in primary bile reflux gastritis. Methods:Sixty-two patients with primary bile reflux gastritis were randomly divided into 2 groups. Liuweianxiao capsule 3 three times daily for 4 weeks was given to 32 patients in the medical group ,while mosapride citrate 5mg three times daily for 4 weeks to 30 patients in the control group. Dyspepsia symptoms were evaluated during visit before and 4 weeks after treatment. The clinical effect and side effects were compared between 2 groups. Results:After 4 weeks of treatment,the symptoms including stomachache, heartburn, abdominal distention, belching, nausea or vomiting bile in patients with primary bile reflux gastritis in beth medical group and control group had been improved. The total effective rate of medical group was 90.62%.The total effective rate of control group was 93.33%. There was no significant difference in the total effective rate after 4 weeks of treatment between 2 groups(P〉0.05). No serious side effects were found in 2 groups.Condusion:Liuweianxiao capsule is an effective and safe medicine in the treatment of primary bile reflux gastritis.
出处 《现代医药卫生》 2008年第12期1754-1755,共2页 Journal of Modern Medicine & Health
关键词 原发性胆汁反流性胃炎 六味安消胶囊 枸橼酸莫沙比利 Primary bile reflux gastritis Liuweianxiao capsule Mosapride citrate
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