142例糖尿病肾病临床分析

Clinical analysis of 142 cases of diabetic nephropathy

目的:探讨糖尿病肾病(DN)的临床表现及危险因素。方法:收集我院2001年10月～2007年10月诊治的糖尿病患者398例,按1997年美国糖尿病协会(ADA)糖尿病诊断和分型标准确定研究对象DN 142例。利用回顾性研究方法分析DN的病例资料和临床规律;并根据是否伴发肾病将DN分为单纯糖尿病组和糖尿病肾病组,探讨DN的危险因素。结果:142例DN中,未按时服用降糖药46例,高蛋白饮食52例,肥胖78例,高血压51例和糖尿病史≥10年64例,两组间比较差异有统计学意义(P<0.05)。结论:未按时服用降糖药、高蛋白饮食、肥胖、高血压和糖尿病史≥10年是DN的危险因素。

Objective ：To study the clinical manifestations and dangerous factors of diabetic nephropathy （DN）.Methods：One hundred and forty-two patients with DN who were derived from three hundred and ninety-eight patients with diabetic menitus（DM） from October 2001 to October 2007 treated in our hospital according to the standard of diagnosis and typing in ADA, 1997 were regarded as object of study. It was to analyze the case information and clinical regularity with the way of retrospective research, and they were divided into simple DM and DN on the possibility of nephropathy to study the dangerous factors of DN.Results：Among them,forty-six cases didn＇t take medicine on time and fifty-two cases were in high protein diet, seventy-eight in fat,fifty-one in hypertension,sixty-four in DM medical history beyond ten years.Significant difference was observed between them （P〈0.05）.Conclusion：Unregular administration, high protein diet,fat,hypertension,DM medical history beyond 10 years,and all that could be the dangerous factors of DN.