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OX40/OX40L与急性冠状动脉综合征 被引量：2

OX40/OX40L and Acute Coronary Syndrome
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摘要 急性冠状动脉综合征为一类慢性炎症性疾病,T细胞的激活是急性冠状动脉综合征的形成和发展的重要因素。OX40/OX40L是机体炎症反应中一对重要的信号通路,它们相互作用能促进CD4+T细胞的活化、增殖、迁移,因此OX40/OX40L可能参与急性冠状动脉综合征的形成。 Acute coronary syndrome （ ACS ） is a chronic inflammatory disease and T cell activation is an important factor in this process. OX40 and OX40 ligand mediated signaling is important in co-activation of CD4 ＋ T cells and facilitates B-T cell interaction. OX40/ OX40L can provide co-stimulatory signals and has been implicated in the onset and progression of ACS.
作者 古天明 张雪妍 刘运德
机构地区 成都大学医护学院
出处 《心血管病学进展》 CAS 2008年第3期455-457,共3页 Advances in Cardiovascular Diseases
关键词 OX40 OX40L 炎症 急性冠状动脉综合征 OX40 OX40L inflammation acute coronary syndrome
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献16

  • 1Latza U, Durkop H, Schnittger S, et al. The human OX40 homolog: cDNA structure,expression and chromosomal assignment of the ACT35 antigen[ J ]. Eur J Immunol, 1994,24:677.
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二级参考文献21

  • 1Latza U,Durkop H,Schnittger S,et al. The human OX40 homolog:cDNA structure, expression and chromosomal assignment of the ACT35 antigen[J]. Eur J Imunol, 1994,24:677.
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心血管病学进展
2008年 第3期

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