期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

缺氧预处理预防大鼠手术后疲劳综合征的研究 被引量：1

THE EFFECT OF HYPOXIC PRECONDITIONING ON RATS' MODEL OF POSTOPERATIVE FATIGUE SYNDROME
下载PDF
导出
摘要 [目的]探讨缺氧预处理对大鼠手术后疲劳综合征模型的作用并对其作用机制进行初步的探讨。[方法]建立大鼠手术后疲劳综合征模型,观察缺氧预处理对大鼠体力活动及血清超氧化物歧化酶和丙二醛水平的影响。[结果]缺氧预处理能改善模型术后大鼠的活动能力。同时,缺氧预处理组大鼠血清超氧化物歧化酶水平明显升高,丙二醛水平明显降低。[结论]缺氧预处理可提高大鼠的抗氧化能力,对手术后疲劳综合征有明显的改善作用。 [Objective] To observe the effects of hypoxic preconditioning （HCP） on rats＇ model of postoperative fatigue syndrome （POPS） and to study its mechanism. [Methods] After developing rats＇ model of POPS, the rats in HCP group were carried out hypoxic preconditioned for 7 days. The behavioral change, SOD and MDA before and after operation were observed. [Results] HCP could improve the activity of rats. At the same time, rats＇ SOD level advanced, MDA level reduced in HCP group. [Conclusion] HCP can alter enzymatic antioxidant activity and obviously improve POFS.
作者 王玉
机构地区 成都体育学院运动医学系
出处 《现代预防医学》 CAS 北大核心 2008年第10期1907-1908,1910,共3页 Modern Preventive Medicine
关键词 手术后疲劳综合征 缺氧预处理 超氧化物歧化酶 丙二醛 Postoperative fatigue syndrome Hypoxic preconditioning SOD MDA
分类号 R619 [医药卫生—外科学]
  • 相关文献

参考文献12

  • 1Rubin GJ. Hotopf M. Systematic review and meta-analysis of interventions for postoperative fatigue [J]. Br J Surg, 2002, 89 (8): 971-984.
  • 2Murry CE, Jenning RB, Reimer KA, et al. Preconditioning with ischmia: a delay of cell injury in ischemic myocardium [J]. Circulation, 1986, 74: 1124-1136.
  • 3杨建新,邓时贵,杨明,邱幸凡,张六通.大鼠手术后疲劳综合征模型的建立及其评价[J].中国普外基础与临床杂志,2004,11(5):424-427. 被引量：8
  • 4ChandraM, Surendra K, Kapoor RK, et al. Oxidant stress mechanisms in heart failure[J]. Boll Chim Farm, 2000, 139 (3): 149- 152.
  • 5Christensen T, Kehlet H.Postoperative fatigue [J]. World J Surg 1993, 17 (2): 220-225.
  • 6Salmon P, Hall GM. A theory of postoperative fatigue [J]. J R SocMed, 1997, 90 (12): 661-664.
  • 7Tsutui H. Oxidative stress in heart failure: the role of mitochondria [J]. Intern Med, 2001, 40 (12): 1177-1182.
  • 8Glosli H, Tmnstad K J, Wergedal H, et al. Human TNF-alpha in transgenic mice induces differential changes in redox status and glutathione-regulating enzymes [J]. FASEB J, 2002, 16 (11) : 1450-1452.
  • 9Malaplate-Armand C, Gueguen Y, Bertrand P, et al. U373-MG response to interleukin-1 beta-induced oxidative stress[J ]. Cell Biol Toxicol, 2000, 16 (3): 155-163.
  • 10Ihnken K, WinklerA, Schlensak C, et al. Normoxic cardiopulmonary bypass reduces oxidative myocardial damage and nitric oxide during cardiac operations in the adult [J]. J Thorac Cardiovasc Surg, 1998, 116 (2): 327-334.

二级参考文献31

  • 1艾华,陈吉棣,贺师鹏.力竭性游泳对大鼠睾丸金属结合蛋白的诱导及其与睾酮和锌的关系[J].中国应用生理学杂志,1994,10(2):117-120. 被引量：16
  • 2陈长勋,金若敏,李仪奎,黄坚,钟健,张晓晨,张海桂.正常SD大鼠的部分生物数据测定[J].动物学杂志,1996,31(4):19-22. 被引量：15
  • 3李卫平 田中 李晓霞.“我国田径耐力性项目模拟高原训练的研究”课题结题报告[R].,2003..
  • 4浅野胜己.高原训练的生理学意义和最新动向[J].临床运动医学,1999,16:505-505.
  • 5Stray - Gundersen J, Chapman RF, Levine BD. "Living high -training low" altitude training improves sea level performance in male and female elite runners. J Appl Physiol, 2001, 3 : 1113-1120.
  • 6Hiller WD, Fortess EE, Wong DL, et al. Live high - training low affects endurance factors in some athletes. Med Sci Sports Exerc, 2000, 32: 1220.
  • 7Lee KC, Asano K, Hu Y. Effects of combining of an exercise training and an exposure to hypoxia on growth rate, food intake, oxygen transporting capacity, muscle oxidative capacity,and exercise performance in rats. Adv Exerc Sports Physiol,1999, 5:71 - 77.
  • 8Vogt M, Billeter R, Hoppeler H. Effec't of hypoxia on muscular performance capacity. Ther Umsch, 2003,7:419- 424.
  • 9Stray - Gundersen J. Living high and training low can improve sea level performance in endurance atttletes. Proceeding of The 2n':l International Symposium on High Altitude Training'99 Tsukuba. 1999,8- 18.
  • 10Yang Hu, Zhaowei Kong, Haiping Liu. Effects of hypoxic training on aerobic capacity and performance. High Altitude Training Symposium, Hong Kong 2004.

共引文献96

同被引文献19

引证文献1

二级引证文献9

现代预防医学
2008年 第10期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部