不同浓度含氟涂膜对乳牙防龋效果的临床研究

CLINICAL RESEARCH ON THE EFFECT OF DIFFERENT CONCENTRATIONS OF FLUORIDE VARNISH ON PREVENTION OF CARIES IN DECIDUOUS TEETH

[目的]评价3种不同浓度含氟涂膜的防龋效果。[方法]420例3～5岁儿童分4组:对照组及0.2%、0.5%、1%含氟涂膜组。实验组儿童每半年涂氟1次,共两次,对照组不采取任何措施。[结果]实验前各组的患龋率、龋失补牙数(dmft)、龋失补牙面数(dmfs)无统计学差异(P﹥0.05)。1年后实验组的新增患龋率、dmft、dmfs均低于对照组,1%含氟涂膜组与对照组间差异有统计学意义(P﹤0.05),其他组间无统计学差异(P﹥0.05)。[结论]含氟涂膜具有防龋的功效,1%含氟涂膜防龋效果优于0.2%和0.5%含氟涂膜。

[ Objective] To evaluate the effect of three concentrations of fluoride varnish on prevention of caries. [ Methods] 420 children at the age of 3 to 5 years were divided into four groups： control group, children respectively treated with 0.2%, 0.5% and 1% fluoride varnish concentration. Children in experiment group were fluoridized one time for every half a year, continuously for two times, but not any measure was taken to the control group. [ Results] No significantly difference was found among the caries prevalence rates and the values of dmft and dmfs in every group before treatment （P 〉 0.05）. The newly caries prevalence rates and the values of dmft and dmfs among the experimental groups after one year were significantly decreased when compared with control group, and significantly difference was found between the children treated with 1% fluoride varnish concentration （P 〉 0.05）. No significantly difference was found among other groups （P 〉 0.05）. [Conclusion] Fluoride varnish is effective in prevention of caries, the effect of fluoride varnish with 1% fluoride is better than that with 0.5% and 0.2% fluoride.