子宫肌瘤基因芯片的研究

Study on gene chip of leiomyoma of uterus

基因芯片是一种能快速检测大量基因表达的分子生物学研究工具。子宫肌瘤基因芯片的研究发现,肌瘤中与细胞生长、增殖、凋亡、代谢、细胞运动性、血管发生、细胞外基质形成、细胞分化和免疫相关的基因表达发生了改变。文章综述子宫肌瘤基因芯片的研究进展,从分子水平探讨子宫肌瘤的发病机制。

Gene chip is a research tool on molecular biology which can detect generous gene expression rapidly. The studies on gene chip of leiomyoma have revealed the changes of gene expression related to cell growth, proliferation, apoptosis, metabolism, angiogenesis, formation of extracellular matrix, cell differentiation and immunity. The article reviews the advance on gene chip of leiomyoma and approaches the pathogenesis of leiomyoma on molecular level.