再次肾移植52例特征分析

Characteristics of renal retransplantation in 52 cases

选择1998-05/2006-12于解放军第三军医大学大坪医院野战外科研究所泌尿外科施行再次肾移植的患者52例,回顾性分析两次移植手术间隔时间、再次移植术前是否切除原移植肾、是否给予免疫诱导治疗、术后不同免疫抑制剂方案、术后急性排斥反应发生情况以及人/肾存活率等资料。结果显示,再次肾移植的手术时机无明显限制,条件允许可在再次移植时同时切除失功移植肾;术前抗体诱导治疗可有效预防术后急性排斥反应的发生。

A retrospective analysis was conducted in 52 cases who received renal retransplantation in the Department of Urology, Research Institute of Surgery, Daping Hospital, the Third Military Medical University of Chinese PLA from May 1998 to December 2006. All the patients were analyzed according to the interval between the first and the second transplantations, nephrectomy of the previous graft, use of immunity induction therapy and different protocols of immunosuppressant, and the clinical data, such as the incidence of acute rejection and the survival rates of patients and grafts. Results revealed that, the time of retransplantation is unlimited, and nephrectomy of the previous graft can be performed at the same time of retransplantation. Preoperative antibody-inducing therapy can effectively prophylaxis acute rejection.