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新辅助化疗治疗晚期乳腺癌56例

Neoadjuvant Chemotherapy in Treatment for 56 Cases with Advanced Breast Cancer
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摘要 [目的]评价经典的CAF新辅助化疗方案治疗乳腺癌的价值。[方法]选择初诊不可手术的乳腺癌患者56例,采用环磷酰胺(CTX)+阿霉素(ADM)+5-氟尿嘧啶(5-Fu)作为新辅助化疗方案,21d为1个周期,2~4个周期,以国际抗癌联盟(UICC)标准评定近期疗效,并镜下观察原发灶细胞形态学变化。[结果]39例临床分期降低,腋窝淋巴结肿大消失或缩小28例。临床完全缓解(CR)30.35%,部分缓解(PR)53.57%,稳定(SD)14.28%,进展(PD)1.79%。病理完全缓解(CR)3.57%,部分缓解(PR)82.14%,无效(NR)14.29%,[结论]CAF作为新辅助化疗方案有确切疗效,使不可手术的乳腺癌患者重新获得手术,临床疗效与病理疗效评估不尽一致。
机构地区 博爱县人民医院
出处 《肿瘤学杂志》 CAS 2008年第5期405-406,共2页 Journal of Chinese Oncology
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