急性期脉压对脑梗死近期预后的影响

Effect of pulse pressure level on the short-term prognosis of patients with acute cerebral infarction

目的探讨脉压对急性脑梗死患者近期预后的影响。方法连续收集急性脑梗死住院患者286例,通过动态血压检测计算出急性期脉压,经过3个月随访观察评价脑梗死患者近期预后。结果不同脉压脑梗死患者3个月后日常生活活动能力(ADL)、改良Rankin量表(mRS)值及死亡率不同,脉压愈大脑梗死患者预后愈差,脉压≥81mmHg组患者与≤60mmHg组患者间差别有统计学意义(P<0.05)。结论脑梗死急性期脉压增高患者3个月后预后差。

Objective To investigate the effect of pulse pressure （PP） level on the short-term prognosis of patients with acute cerebral infarction. Methods We consecutively recnxited 286 patients with aeute cerebral infarction, ambulatory blood pressure monitoring （ABPM） was performed to calculate the PP. All patients were followed-up prospectively and the death events, value of activities of daily living （ADL） and modify rankin scale （mRS） was evaluated. Results Elevated PP was associated with poor outcome by mortality, ADL and mRS. Those outcome were significantly different between patients with PP more than 81mmHg and those less than 60mmHg （P〈0.05）. Conclusion Elevated PP is associated with poor stroke outcome at 3 months at patients with acute cerebral infarction.