275例中药制剂不良反应报告分析

ADRs Induced by Chinese Materia Medica Preparation:Analysis of 275 Cases

目的：促进临床合理用药。方法：对四川雅安市2005-2007年药品不良反应（ADR）监测中心收集到的275例中药制剂ADR报告进行分类统计、分析。结果：2005年56例中药制剂ADR中，中药注射剂占总例数的80．4％；2006年113例中药制剂ADR中，中药注射剂占总例数的79．8％；2007年106例中药制剂ADR中，中药注射剂占总例数的75．5％。中药注射剂是引起ADR的主要剂型。结论：及时报告中药制剂ADR，加强对其监测与研究，有助于减少和避免中药制剂ADR的发生，保障患者用药安全。

OBJECTIVE： To promote rational drug use in the clinic. METHODS： 275 ADR case reports collected by ADR monitoring center of Yaan city from 2005 to 2007 were classified and analyzed statistically. RESULTS：The occurrence of ADR induced by Chinese materia medica preparations through 1V in 2005 accounted for 80.4% of the total（56 cases）.The occurrence of ADR induced by Chinese materia medica preparations through IV in 2006 accounted for 79.8% of the total（113 cases） .The occurrence of ADR induced by Chinese materia medica preparations through IV in 2007 accounted for 75.5% of the total（106 cases） .The Chinese medicinal injection was the chief dosage form causing ADR. CONCLUSION： Timely reporting of Chinese materia medica preparations - induced ADRs, strengthened monitoring and research of which may help to reduce and avoid the ADRs incidence induced by Chinese materia medica preparations and ensure patients＇ medication safety.