西地那非联合认知行为疗法治疗勃起功能障碍

Therapy effect of silaenafil combination with cognitive behavior therapy on patients with erectile dysfunction

目的评价西地那非联合认知行为疗法治疗勃起功能障碍的疗效。方法将87例从未接受西地那非治疗的勃起功能障碍患者随机分为联合治疗组和单独用药组。联合治疗组42例，年龄25—49岁，平均32岁，病程2.8～5.6年，平均4．2年；单独用药组45例，年龄28—45岁，平均35岁，病程4.8—8.6年，平均5．6年。联合治疗组在医院首次口服西地那非100mg后接受视听觉性刺激，同时进行阴茎勃起硬度实时监测，随后医生对患者讲解测定结果。单独用药组在院外首次服用西地那非100mg，未接受医生的认知辅导。结果联合治疗组的有效率为92，9％（39／42），复诊率83．3％（35／42）；单独用药组的有效率为28．9％（13／45），复诊率15．6％（7／45），两组间的治疗有效率和复诊率均有显著性差异（P〈0.005）。结论西地那非联合认知行为疗法治疗勃起功能障碍效果优于单独西地那非治疗。

Objective To evaluate the efficacy of the combined therapy with silaenafil and cognitive behavior therapy in patients with erectile dysfunction （ED） . Methods A total of 87 patients of ED who had never received the medication of silaenafil before were randomizedly divided into 2 groups. In the Group A 42 patients （ mean age 32 years, mean period of ED 4. 2 years） took silaenafil 100 mg, and soon received cognitive behavior therapy in hospital. Group B 45 patients （mean age 35 years, mean period of ED 5.6 years） took silaenafil 100 mg only. Results In 63 patients （35 males and 28 females, mean age 60. 8 years ） with NIDDM and in 22 normal subjects （ 14 males and 8 females, mean age 56. 0 years ） . There was a significant positive correlation between levels of TF and BUN （r =0. 84, P 〈0. 0001 ） or creatinine （r = 0. 93, P 〈0. 0001 ） .