摘要
目的观察高血压病患者血清C反应蛋白(c-reactive protein,CRP)浓度的变化和关系。方法选择139例高血压病患者和122例健康对照者测定血清CRP浓度、总胆固醇(cholesterol,CHOL)浓度、甘油三脂(triglyeride,TG)浓度、低密度脂蛋白(low density lipoprotein-cholesterol,LDL-C)浓度,比较高血压组和正常血压组及不同血压水平组间血清C-反应蛋白浓度差异。结果高血压组与正常血压组血清C反应蛋白浓度分别为(5.76±0.33)mg/L和(2.63±0.17)mg/L(P<0.001),血清CRP浓度随着血压级别的增加而增加(P<0.05)。结论血清CRP浓度与高血压相关,表明炎症反应参与了高血压病的发生和发展。
[Objective] To study the changes and relationships of C-reactive protein concentration （CRP） in hypertension patients. [Methods] The serum CRP concentration, total cholesterol concentration （Chol）, triglyceride concentration （TG）, low density lipoprotenin cholesterol （LDL-C） were measured in 139 patients with hypentension, compared with the healthy control growp （n =122） and different blood pressure levels. [Reswlts] The serum CRP concentration were （5.26±0.33） mg/L and （2.63±0.17） mg/L in hypertensive group and healthy control group （P 〈 0.001）. The serum CRP concentration rises with the blood pressure level （P 〈0.05）. [Conclusion] Serum CRP concentration is associated with hypertension. Inflammatory response play an important role in the pathogenesis of hypertension.
出处
《中国医学工程》
2008年第1期43-45,共3页
China Medical Engineering
关键词
高血压病
C反应蛋白
炎症
C-reactive protein
hypertension
inflammatory response
