白芍药材的提取纯化工艺研究

目的:通过对白芍药材的提取纯化工艺的研究,确定了最佳的提取纯化工艺务件。方法:采用正交试验进行了醇提取工艺的研究,再采用大孔吸附树脂法进行了纯化工艺研究。结果:以70%乙醇提取三次,时间为(90min,90min,90min)及加醇量为(8倍,8倍,8倍)条件下白芍总苷的收膏率最高,提取液上树脂后先以水洗除去杂质,再收集全部30%的乙醇洗脱液即为白芍总苷的有效部位。结论:采用此工艺可以达到白芍药材的提取、纯化的目的,为其工业化生产应用奠定了科学的基础。

Objective： through white peony material＇s extraction and purification of the study to determine the best conditions for the extraction and purification process. Methods： orthogonal test that the alcohol having been in progress extracts the handicraft research, adopt macroporous resin method on the purification process again. Results： 70% Alcohol extracts a triple , time is （90 min, 90min, 90min）, and increase the volume of alcohol （8 times 8 times 8 times ） under the conditions, Peony glucoside＇s rate is the highest After the first washing to remove impurities, then collect all the 30% ethanol eluate, which is the effective parts of peony material＇s General glucoside. Conclusion： This process can be achieved peony material＇s extraction and purification of the purpose of their industrial production for the application of the scientific basis.