膀胱肿瘤患者尿中表皮生长因子测定

Determination of EGF in urine of patients with bladder tumor

用放射免疫分析法，对３５例正常人和３０例手术前后的膀胱肿瘤患者尿中表皮生长因子（ＥＧＦ）含量为进行测定。结果：膀胱肿瘤患者术前ＥＧＦ含量为（２２．０６±１２．０５）μｇ／Ｌ，显著低于正常人群（３５．６９±２０．０８）μｇ／Ｌ（Ｐ＜０．０５），而膀胱肿瘤患者术后与正常人群相比，ＥＧＦ水平无显著差别。提示膀胱肿瘤无自分泌ＥＧＦ现象，尿中ＥＧＦ有促进肿瘤生长作用。

sing radioimmunoassay,we examined the EGF levels in the urine from 35 normal persons and 30 patients with bladder tumor.The results indicated that before operation the EGF levels in the urine from the patients with bladder tumor((2206±1205) μg/L) were significantly lower(P<005) than those from the normal((35.69±20.08) μg/L),but after operation there was no difference (P>005)between normal persons and operated patients with bladder tumor((39.42±16.32) μg/L).It was concluded that there was no autosecretory phenomenon in bladder tumor.