摘要
目的:观察炎琥宁联合西咪替丁治疗婴幼儿轮状病毒肠炎的疗效。方法:对符合婴幼儿轮状病毒肠炎的临床诊断标准的103例患儿随机分为观察组及对照组,观察组51例,对照组52例。两组均予补液,维持水电解质酸碱平衡,微生态疗法(妈咪爱)及肠黏膜保护剂(思密达)等常规治疗。对照组给予病毒唑10~15mg/(kg·d),加入葡萄糖静脉滴注,每天1次,连续3d。观察组给予炎琥宁10mg/(kg·d)及西咪替丁10-20mg/(kg·d)静脉滴注,每天1次,连续3d。观察两组患儿治疗后退热及止泻时间等疗效。结果:观察组的退热时间、止泻时间均明显短于病毒唑对照组;观察组有效率为92.2%,较对照组的82.7%高,有显著性差异(P均〈0.05)。结论:炎琥宁联合西咪替丁治疗婴幼儿轮状病毒肠炎的疗效优于病毒唑。
dium dehydroandroan Objective: To investigate the effects of treating infantile rotavirus enteritis with potassium sodrographolide succinate and cemitidine. Methods: One hundred and three infantile patients diagnosed as rotavirus enteritis according to clinical diagnostic criteria were divided randomly into trial group (n = 51 ) and control group( n = 52). On the base of treated all patients routinely with replenishment of liquid, maintaining balance of water-electrolyte, acid and base, undergoing therapy of microorganisms with medial - vita and protection of gastrointestinal mucosa with smecta; patients in control group treated with ribavirin 10~15 mg/(kg·d) diluted with glucose solution intravenously, once a day for 3 days. Patients in trial group treated with potassium sodium dehydroandroan drographolide succinate 10 mg/(kg·d) and cimetidine 10~20 mg/(kg·d) intravenously, once a day for 3 days. Effects of abating fever and anti - diarrhea were observed. Results: The time of fever ceasing and diarrhea control in trial group was shorter than that in control group; the effectuate rates of the trial group and control group were 92.2% and 82.7% respectively, compared them, there were significant differences( all P〈 0.05 ). Conclusion: The effects of treating infantile rotavirus enteritis with potassium sodium dehydroandroan drographolide succinate and cemitidine is better than that of ribavirin.
出处
《海南医学院学报》
CAS
2008年第3期260-261,264,共3页
Journal of Hainan Medical University
关键词
肠炎
病毒
西咪替丁
中草药
儿童
Enteritis
Virus
Cimetidine
Chinese herbal
Children