慢性非细菌性前列腺炎患者前列腺液中性激素水平的研究

Study of Sexual Hormones in Prostatic Fluid from Patients with Chronic Abacterial Prostatitis

目的:探讨性激素睾酮(Testo)、雌二醇(E2)、泌乳素(PRL)在慢性非细菌性前列腺炎(CPPS)发病机制中的作用。方法:采用化学发光免疫分析法(CIA)检测50例慢性前列腺炎患者和20例健康体检者的前列腺液中的性激素水平。结果:慢性前列腺炎组睾酮(Testo)水平比对照组明显下降(P<0.05),雌二醇(E2)水平明显升高(P<0.01),均具有显著性意义;泌乳素(PRL)水平无明显差异。结论:性激素分泌失衡与慢性非细菌性前列腺炎(CPPS)的发生发展有密切关系;但其具体机制尚需进一步研究。

Objective： To investigate the role of sexual hormones in pathogenesis of chronic abacterial prostatitis. Methods： Levels of testosterone（T）, estradiol（E2） and prolactin（PRL） were detected by chemiluminescence immunoassay（CIA） in 50 patients with CAP and 20 controls. Results： The levels of T was lower than that in the controls （ P 〈 0.05 ）. The levels of E2 in the patients was significandy higher than that in controls （P 〈0.01 ）. There was no significant difference between the patients and normal controls in the levels of PRL. Conclusion： The Disequilibrium of sexual hormones were involved in the pathogeny and development of CAP, but it＇s needed to furhtur investigate in the specific pathogenesis.