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蛋白质结构预测方法研究 被引量:1

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摘要 蛋白质等大分子的结构和功能的预测是生命科学研究的主要内容之一,一个特定的蛋白质的功能通常是由它的三维结构或构象决定的。就蛋白质结构预测方法进行简速,目的是更好的为下一步的蛋白质结构预测研究提供方便,同时也强调了蛋白质结构预测对生物制药的重要作用。
出处 《黑龙江科技信息》 2008年第19期44-44,共1页 Heilongjiang Science and Technology Information
基金 辽宁省教育厅资助项目(NO:20060018)
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  • 1GUNSALUS I C, LPEDERSON T C ,SLIGAR S G. Oxygenase-catalyzed biological hydroxylations[J]. Annual Review of Biochemistry, 1975 ,44 (1) :377-407.
  • 2ORTIS de MONTELLA NO P R. Cytochrome P450 : Structure, Mechanism, and Biochemistry[M]. 2nd ed. New York : Plenum, 1995.
  • 3PORTER T D, COON MJ. CytoehromeP450: Multiplicity of isoforms, substrates, and catalytic and regulatory mechanism[J].Journal of Biology Chemistry, 1991,266(21) : 13459-13472.
  • 4WEN L P, FULCO A 1. Cloning of the gene encoding a catalytically self-sufficient cytochrome P- 450 fatty acid monooxygenase induced by barbiturates in Bacillus megaterium and its functional expression and regulation in heterologous (Escherichia coli) and homologous (Bacillus megaterium) hosts[J].Journal of Biological Chemistry, 1987 ,262 ( 14) :6676-6682.
  • 5BELL S G, HARDORD-CROSS C F, WONG L L. Engineering the CYPIOI system for in vivo oxidation of unnatural substrates[J]. Protein Engineering, 200 1 , 14 ( 10) : 797 -802.
  • 6SCHEW H, KAUP B A, SCHRADERJ. Improvement of P450BM-3 whole-cell biocatalysis by integrating heterologous cofactor regeneration combining glucose facilitator and dehydrogenase in E. coli[J]. Applied Microbiology and Biotechnology ,2008,78 (1) :55-65.
  • 7CANMEHAEL A B, WONG L L. Protein engineering of Bacillus megaterium CYPI02 : The Oxidation of Polycyclic aromatic hydrocarbons[J]. EuropeanJournal of Biochemistry,2001 ,268( 10) :3117-3125.
  • 8SCHNEIDER S, WUBBOLTS M G, SANGLARD D, et al. Production of chiral hydroxyl long chain fatty acids by whole cell biocatalysis of pentadecanoic acid with an E. coli recombinant containing cytochrome P450 BM-3 monooxygenase[J]. Tetrahedron: Asymmetry, 1998,16 (9) : 2832-2844.
  • 9LI Q S, SCHW ANEBERG U, SCHMID R D. Directed evolution of the fatty-acid hydroxylase P450 BM-3 into an indolc-hydroxylating catalyst [J]. Chemistry ,2000 ,6( 9) : 1531-1536.
  • 10SCHWEDE T ,KOPPJ, GUEX N ,et al. Swiss-Model: An automated protein homology-modeling server[J]. Nucleic Acids Research ,2003 ,31 (13) :3381-3385.

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