常规检测孕产妇及婴幼儿人类免疫缺陷病毒抗体的临床意义

Clinical significance of conventional detection of maternal and infant anti-HIV antibody

目的研究对孕产妇及婴幼儿进行人类免疫缺陷病毒（HIV）抗体常规检测的临床意义。方法用酶联免疫吸附试验对48450例患者血清进行HIV抗体初筛试验，阳性者送甘肃省疾病预防控制中心确认。结果2000-2007年，初筛阳性19例，确认阳性12例，HIV抗体检测不确定4例，阴性3例。12例阳性中，5～9岁儿童占6例，16-53岁占6例。结论甘肃省孕产妇和婴幼儿HIV感染已时有发生，为防止疾病扩散，应早发现、早治疗。针对孕产妇和婴幼儿开展HIV抗体常规检测具有十分重要的临床意义和社会意义。

Objective To investigate the clinical significance of conventional detection of maternal and infant anti-HIV antibody. Methods Enzyme-linked immunosorbent assay was applied to performing anti-HIV antibody preliminary screening test for 48 450 eases of patients serum samples, and the positive results were confirmed by the Centre for Disease Control and Prevention of Gansu Province. Results From the year of 2000 to 2007, the preliminary screening positive samples were 19 cases, confirmed positive samples 12 cases, uncertain samples 4 cases, and anti-HIV antibody negative samples were 6 cases. In the 12 eases of confirmed patients, 5- to 9-year-old children and 16- to 53- subjects accounted for a half respectively. Conclusion Occurrence of maternal and infant HIV infection in Gansu Province is frequent. Early detection and prompt treatment should be strengthened to prevent the spread of the disease. Anti-HIV antibody conventional detection aiming directly at maternal and infant possesses a vital clinical and social significance.