肾上腺髓质素在肾病领域研究进展
摘要
1993年日本学者Beltowski等在肾上腺髓质起源的人嗜铬细胞瘤中发现并分离出一种新的降血压多肽,命名为肾上腺髓质素(adrenomedullin,AM)。AM在人和啮齿类动物体内广泛分布,具有舒张血管、降低血压、排钠利尿、抑制器官纤维化、调节细胞增殖分化迁移、抗感染和炎症调节等生物学作用。本文就肾上腺髓质素的特点及其与肾脏疾病的关系作一综述。
出处
《临床肾脏病杂志》
2008年第4期185-188,共4页
Journal Of Clinical Nephrology
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