摘要
目的:探讨性视频刺激加5型磷酸二酯酶(PDE5)抑制剂激发阴茎勃起实验在勃起功能障碍(ED)诊治中的应用价值,以指导ED的诊断和治疗。方法:收集门诊ED患者853例,分为损伤和非损伤两组,先应用国际勃起功能评分5问卷表(IIEF-5)评分,口服PDE5抑制剂30min后再予性视频刺激,通过阴茎硬度监测仪实时监测阴茎勃起。结果:损伤组中轻度、中度和重度ED患者分别占18.8%、31.9%、49.3%,非损伤组中分别占50.6%、39.8%、9.6%,两组患者轻、重度ED的比例差异有显著性(P<0.05);性视频刺激加PDE5抑制剂激发阴茎勃起实验结果损伤组中显效、有效和无效分别占13.0%、14.5%、72.5%,总有效率为27.5%,而非损伤组中分别占55.7%、20.7%、23.6%,总有效率为76.4%,两组患者总有效率比较有统计学意义(P<0.05)。结论:利用性视频刺激加PDE5抑制剂激发阴茎勃起实验鉴别心理性ED和器质性ED,方法简单,实用,准确性高,可作为ED的初筛试验,值得推广应用。
Objective: To evaluate the type V phosphodiesterase (PDE-5)inhibitor erection-provoking test with audio-visual sexual stimulation in the diagnosis of erectile dysfunction. Methods : A total of 853 out-patients diagnosed with erectile dysfunction were divided into an injury and a non-injury group. After scored on IIEF-5 questionnaires, all the patients received oral administration of PDE- 5 inhibitors and, 30 minutes later, audio-visual sexual stimulation. The data on penile erection were recorded with Rigiscan Plus. Results: The patients with mild, moderate and severe ED accounted for 18.8, 31.9 and 49.3 % in the injury group, and 50.6, 39.8 and 9.6% in the non-injury group, with statistic differences between the two groups in the mild and severe parts ( P 〈 O. 05 ). The rates of conspicuous effectiveness, effectiveness, ineffectiveness and total effectiveness of the combined method were 13. 0, 14.5, 72.5 and 27.5 % in the injury group, but 55.7, 20.7, 23.6 and 76.4% in the non-injury group, with significant differences (P 〈 O. 05).Conclusion: The PDE-5 inhibitor erection-provoking test with audio-visual sexual stimulation is a simple, practical, safe and effective method for the differentiation of organic from psychological erectile dysfunction.
出处
《中华男科学杂志》
CAS
CSCD
2008年第5期445-447,共3页
National Journal of Andrology