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全胃切除术后不同营养支持方式对患者免疫功能的影响 被引量:1

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摘要 目的探讨全胃切除术后不同营养支持方式对患者免疫功能的影响。方法选择行全胃切除术患者33例,随机分为肠内营养组(17例,EN组)和肠外营养组(16例,PN组),分别于手术前后检测外周血补体和免疫球蛋白水平及各种淋巴细胞百分率的变化,并观察感染性并发症发生率及胃肠功能恢复时间。结果术后第1天.两组患者补体、免疫球蛋白及淋巴细胞百分率均较术前明显下降(P〈0.05);而术后第8天,EN组补体及免疫球蛋白水平较术后第1天有所恢复(P〈0.01),且改变量与PN组比较差异有统计学意义(P〈0.05)。术后第8天,两组患者淋巴细胞百分率及EN组的CD4^+/CD8^+较术后第1天有所恢复(P〈0.01);EN组淋巴细胞百分率的改变量与PN组比较差异有统计学意义(P〈0.01)。PN组术后感染性并发症的发生率(31.3%)高于EN组(5.9%)(P〈0.05)。结论全胃切除术后患者EN支持较PN支持能更好地促进免疫功能的恢复,降低肺内感染的发生率。
出处 《中华胃肠外科杂志》 CAS 2008年第3期284-285,共2页 Chinese Journal of Gastrointestinal Surgery
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