期刊文献+

胚胎发育对囊胚移植妊娠结局影响的临床研究 被引量:4

下载PDF
导出
摘要 目的研究胚胎发育对囊胚移植妊娠结局的影响。方法回顾性分析IVF-ET助孕中囊胚培养和移植的60例病例,根据是否妊娠分为2组,妊娠组34例,未妊娠组26例,比较并分析2组正常受精率、第2d卵裂球数量、第3d卵裂球碎片率、第4d紧密化程度和第5d天胚胎发育阶段的差异。结果妊娠组和未妊娠组正常受精率、第2d卵裂球数量、第4d紧密化程度无明显差异,但第3d卵裂球碎片率妊娠组明显低于未妊娠组,而第5d优质囊胚移植率妊娠组也高于未妊娠组,两者比较有显著性差异(P<0.05)。结论第5d天胚胎发育阶段和第3d卵裂球碎片率影响囊胚的植入率,同时通过观察第5d天胚胎发育阶段和第3d卵裂球碎片率来选择优质胚胎移植将有助于提高妊娠率。
出处 《中国优生与遗传杂志》 2008年第5期113-113,112,共2页 Chinese Journal of Birth Health & Heredity
基金 佛山市科技攻关项目(项目编号:03080111)
  • 相关文献

参考文献5

  • 1Schieve LA, Rasmussen SA, Buck GM, et al. Are children born after assisted reproductive technology at increased risk for adverse health outcomes? [ J]. Obstet Gynecol,2004,103 : 1154 - 1163.
  • 2Coetsier T, Dhont M. Avoiding multiple pregnancies in in - vitro fer- tilization: whog afraid of single embryo transfer? [J]. Hum Reprod, 1998,3:2663 - 2664.
  • 3Van Landuyt L, De Vos A, Joris H,et al. Blastocyst formation in vitro fertilization versus intracytoplasmic sperm injection cycles: Influence of the fertilization procedure [ J ]. Fertil Steril,2005, 83 : 1397.
  • 4Papanikolaou EG, et al. Steroid receptor expression in late follicular phase endometfium in GnRH antagonist IVF cycles is already altered, indicating initiation of early luteal phase transformation in the absence of secretory changes [ J ]. Hum Reprod,2005,20 : 1541.
  • 5Wilson M, Hartke BA, Kiehl M, et al. Transfer of blastocysts and morulae on day 5[J]. Fertil Steril, 2004,82:327 - 333.

同被引文献47

  • 1邓捷,彭文林,刘颖,周灿权,李洁,方丛,林雯青,庄广伦,曾艳红,童大跃.应用荧光聚合酶链反应对α地中海贫血进行植入前遗传学诊断[J].中华医学杂志,2005,85(38):2682-2685. 被引量:14
  • 2陈士岭,李劲,孙玲,邢福祺.取卵后第3天胚胎形态学指标与移植后着床的关系[J].实用妇产科杂志,2007,23(2):106-108. 被引量:5
  • 3刘海宁,邵翠华,汤秀明,刘忠强,李强.体外受精-胚胎移植中胚胎碎片对临床妊娠率影响[J].青岛大学医学院学报,2007,43(2):137-138. 被引量:3
  • 4Ko TM ,Tseng LH, Hsieh FJ,et al. Carrier detection and p renatal diagnosis of alpha - thalassemia of Southeast Asian deletion by polymerase chain reaction[ J ]. Hum Genet, 1992,88:245 -248.
  • 5Chamayou S, Alecci C, Ragolia C, et al. Successful application of preimp lantation genetic diagnosis for β2thalassemia and sickle cell anemia in Italy [ J ]. Hum Reprod ,2002,17 : 1158 - 1165.
  • 6PiyamongkolW, Harper JC, Delhanty JD, et al. Preimp lantaton genetic diagnostic protocols for alpha2 and beta - Thalassemias using multiplex fluorescent PCR1 [ J]. Prenat Diagn ,2002,21:752 -759.
  • 7Edwards RG, Beard HK. Oocyte polarity and cell determi- nation in early mammalian embryos. Mol Hum Reprod, 1997, 3(10):863-905.
  • 8White E. Life, death, and the pursuit of apoptosis//Genes Dev. Cold Spring Harbor Laboratory Pres s, 1996,10:1-15.
  • 9Jurisicova A, Varmuza S, Casper RF. Programmed cell deathand human embryo fragmentation. Mol Hum Reprod, 1996, 2(2):93-8.
  • 10Alikani M, Schimmel T, Willadsen SM. Cytoplasmic fragmentation in activated eggs occurs in the cytokinetic phase of the cell cycle, in lieu of normal cytokinesis, and in response to cytoskeletal disorder. Mol Hum Reprod, 2005, 11(5):335-44.

引证文献4

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部