非酒精性脂肪肝患者的生活方式特征研究

Investigation of the lifestyle characteristics in patients with nonalcoholic fatty liver

目的:研究非酒精性脂肪肝人群的患病危险因素以及生活方式特征。方法:单纯性脂肪肝43例,脂肪性肝炎51例,健康体检者74例,分别对其生活状况、体检指标以及行为学特征进行方差和协方差分析。结果:脂肪肝以中年男性居多,体重指数、血压、谷丙转氨酶和甘油三酯均显著高于对照组,年龄性别协方差显示脂肪性肝炎人群体重指数、谷丙转氨酶、血糖、甘油三酯、胆固醇等显著高于单纯性脂肪肝人群。生活状况和行为特征显示脂肪肝人群表现为吃饭过快、运动减少、肌肉酸痛以及不愿与他人交流等(P<0.05),尤其脂肪性肝炎人群对自身体质认识存在明显偏差。结论:脂肪肝人群多伴有三高症状,普遍存在体质认识、摄食行为以及运动不合理等问题,针对性地实施认知行为治疗和科学的运动指导将有助于预防和延缓脂肪肝的发生和进展。

Objective：To investigate the lifestyle characteristics in patients with nonalcoholic fatty liver disease （NAFL）, Method： Patients with simple fatty liver （n=43） and with nonalcoholic steatohepatitis （NASH） （n=51） and healthy control subjects （n=74） were investigated to observe their living conditions, physical examination indexes and behavioral characteristics. These data were analyzed by ANOVA and covariance analysis.Result：The body mass indexes （BMI）, blood pressure and some serum indexes such as ALT, glucose, triglyceride and cholesterol increased significantly in patients with NAFL compared with control subjects. Lifestyle characteristics such as eating fast, little exercises, feeling fatigue and less communication with others in patients with NAFL were significantly higher than that in control subjects. There were significantly misunderstanding on recognitions of constitution in patients with NASH. Conclusion：Most of the patients with NAFL have ＂three high＂symptoms of hyperlipemia, hypertension and hyperglycemia, and have more lifestyle problems in recognition of their own constitution, diet behavior and unreasonable exercises. Both cognitive behavior therapy and scientific exercises counseling may be helpful to prevent occurrence and development of this disease.