两个哒嗪衍生物为配体的铜(Ⅱ)配合物的合成、晶体结构和清除自由基活性(英文)

Synthesis, Crystal Structures and Radical-scavenging Activities of Two Cu(Ⅱ) Complexes with the Ligand Containing Pyridazine Derivatives

本文合成了2个新型Cu(Ⅱ)配合物:[Cu_2(L_1)_2Cl_4]L_1(1)和[Cu(L_2)_2(NO_3)_2(H_2O)](2),其中L_1为3,6-二(苯并三唑-1-)哒嗪,L_2为3-(1,2,4-三氮唑-1-)-6-氯哒嗪。配合物1的晶体属于三斜晶系,P1空间群。铜离子与3个氯原子和配体的2个氮原子形成五配位的四角锥构型,2个氯原子以μ-2方式桥联2个中心铜原子。在配合物1的晶胞中1个游离配体未参与配位。配合物2的晶体属于单斜晶系,C2/c空间群。铜原子处于五配位四角锥配位环境中。分子间氢键将2的分子结构延伸为一维链、二维网状结构,并通过分子间的π-π堆积作用进一步使配合物构型发展成三维拓扑结构。应用邻苯三酚自氧化法对本文所涉及的化合物进行了清除自由基活性测试,结果表明:这2个配体都具有较好的活性。

Two Cu （Ⅱ） complexes, [Cu2（L1）2Cl4]L1 （1） and [Cu （L2）2 （NO3）2 （H2O）] （2） （L1 =3,6-bis-（benzotrizole-yl） pyridazine, L2=3-（1,2,4-triazole-yl）-6-chloro-pyridazine）, have been synthesized and characterized. The complex 1 crystallizes in the triclinic system, P1 space group, the Cu（Ⅱ） ion is in five-coordinated square pyramidal coordinated environment with two N from the ligand and three Cl atoms. Two Cu（Ⅱ） ions are bridging linked by two Cl atoms in μ- 2 model, and there is an uncoordinated ligand molecule in the unit cell of the complex 1. The complex 2 crystallizes in the monoclinic system, C2/c space group, the Cu（Ⅱ） ion is also in a five-coordinated square pyramidal environment with two Nnitrate atoms and three Owater atoms. The configuration of 2 is extended to 1D chain and 2D networks by hydrogen bonds, and then further extended to 3D topological framework via intermolecular π-π stacking action. The radical-scavenging activities of the title compounds have been studied by using the pyrogallol autoxidation method, the results indicate that the ligands present excellent radical-scavenging activities.