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舒芬太尼在老年冠心病病人全麻诱导中对血流动力学的影响 被引量:5

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摘要 目的观察在老年冠心病病人全麻诱导及气管插管过程中应用不同浓度舒芬太尼效应室靶控输注对血流动力学的影响。方法选取择期行冠状动脉旁路移植术(CABG)的病人60例,ASA分级Ⅱ-Ⅲ级。按舒芬太尼效应室靶浓度(Ce)不同将病人随机分为:低浓度组(0.5 ng/ml);中浓度组(0.6 ng/ml)和高浓度组(0.7 ng/ml)。每组20例。分别在麻醉诱导前(T1)、诱导后(T2)、气管插管后1 min(T3)、3 min(T4)记录心率(HR)、收缩压(SBP)、舒张压(DBP)、心输出量(CO)、心脏指数(CI)、SI、体循环血管阻力(SVR)。结果低浓度组血压(BP)和HR在T3和T4时较T1时均明显增高,而高浓度组在T2时BP和HR明显降低(P〈0.05);而中浓度组各时间点没有明显变化。三组间在T2-T4之间存在明显差异(P〈0.05)。低浓度组和中浓度组在各个时间点的CO、CI、SI、SVR均无明显变化;而高浓度组在T2-T4时的上述血流动力学指标较低浓度组均明显降低(P〈0.05)。高浓度组与其他两组之间在T2时存在明显差异(P〈0.05)。结论以Ce0.6 ng/ml浓度进行舒芬太尼效应室靶控输注可安全地用于老年冠心病病人全麻诱导和气管插管,有利于维持血流动力学稳定。
作者 袁治国
出处 《中国老年学杂志》 CAS CSCD 北大核心 2008年第9期895-896,共2页 Chinese Journal of Gerontology
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同被引文献29

  • 1李建玉,辛博,曹云飞,吴新文,颜志伟,迮浩诚.舒芬太尼对0.75%罗哌卡因蛛网膜下腔阻滞效应的影响[J].实用医学杂志,2006,22(2):206-208. 被引量:9
  • 2陈世彪,陈刚.舒芬太尼与芬太尼用于心脏瓣膜置换术全麻诱导的比较[J].江西医药,2006,41(11):842-844. 被引量:1
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