丙种球蛋白与抗生素治疗慢性前列腺炎疗效对比观察

Comparative investigation on the therapeutic effects of Human r-Globulin and antibiotics on chronic prostatitis

目的:探讨静注人丙种球蛋白与抗菌素治疗慢性前列腺炎的效果。方法:选择慢性前列腺炎患者83例,对其中44例单用静注人丙种球蛋白进行治疗(丙球组),对39例应用常规抗生素进行治疗(抗生素组),并分别随访3个月,比较两组的治疗效果。结果:丙球组有效39例,无效5例,有效率为88.6%;抗生素组有效25例,无效14例,有效率为64.1%。结论:由于大多数慢性前列腺炎的病因尚不清楚,治疗效果不甚满意,以往所有的治疗均专注于前列腺局部原因,较少关注全身免疫系统对前列腺的影响。本文结果提示对慢性前列腺炎的治疗应关注全身免疫系统对局部的影响。

Objective： To investigate the therapeutic effects of Human r-Globulin and antibiotics treatment on chronic prostatitis. Methods： 44 cases of chronic prostatitis patients underwent human r-Globulin and 39 patients received routine antibiotics treatment. Then they underwent a follow-up for 3 months respectively to contrast their therapeutic effects in these two groups. Results： Because the clinical presentations of chronic prostatitis changed greatly, we used a NIH-CPSI scoring as an evaluation index. We found in the human r-Globulin intravenous injection group, 39 cases showed effect on their presentations and 5 cases showed no effect, and 25 cases versus14 cases in antibiotics treatment group. Conclusion： Because the etiology of most of the chronic prostatitis is uncleared yet. the therapeutic effect is far from satisfying. The previous therapeutic methods have all focused on the local factors at prostate rather than the influence of general immune system on the organ. The influence of general immune system on the local area should be emphasized during the treatment of chronic prostatitis.